Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...

Filgrastim 💬

Name	Other Names
Filgrastim	Filgrastim (USP/INN) Filgrastim (genetical recombination) (JP18) Filgrastim (genetical recombination) [Filgrastim biosimilar 1] (JAN) Tbo-filgrastim Filgrastim (genetical recombination) [Filgrastim biosimilar 2] (JAN) Filgrastim (genetical recombination) [Filgrastim biosimilar 3] (JAN) Filgrastim-sndz Filgrastim-aafi Neupogen (TN) Nivestym (TN) Grastofil (TN) Zarxio (TN) GRANIX RELEUKO

[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
16	Crow-Fukase syndrome
22	Moyamoya disease
25	Progressive multifocal leukoencephalopathy
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
38	Stevens-Johnson syndrome
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
47	Buerger disease
49	Systemic lupus erythematosus
51	Scleroderma
57	Idiopathic dilated cardiomyopathy
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
96	Crohn disease
113	Muscular dystrophy
164	Oculocutaneous albinism
256	Muscle glycogenosis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
296	Biliary atresia
331	Idiopathic multicentric castleman disease

2

[5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...

Lenograstim 💬

[7] 2, 13, 16, 18, 19, 57, 65 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
13	Multiple sclerosis/Neuromyelitis optica
16	Crow-Fukase syndrome
18	Spinocerebellar degeneration
19	Lysosomal storage disease
57	Idiopathic dilated cardiomyopathy
65	Primary immunodeficiency

3

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

Carvedilol 💬

[4] 57, 86, 113, 210 💬

4

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

[2] 57, 67 💬

5

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

Carvedilol 💬

[4] 57, 86, 113, 210 💬

6

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

[2] 57, 67 💬

7

[7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

Carvedilol 💬

[4] 57, 86, 113, 210 💬

8

[7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...

[2] 57, 67 💬

9

[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...

Carvedilol 💬

[4] 57, 86, 113, 210 💬

10

[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...

Metoprolol 💬

[6] 17, 57, 58, 113, 193, 226 💬

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