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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CYP11A1
💬
1. CYP11A1
×
Name
Full Name
CYP11A1
cytochrome P450 family 11 subfamily A member 1
[6]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
[6]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis
...
Levoketoconazole
Levoketoconazole
💬
1. CYP11A1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
Levoketoconazole
[1]
75
75
💬
1. CYP11A1
×
Disease ID
Name
75
Cushing disease
2
CYP11B1
💬
2. CYP11B1
×
Name
Full Name
CYP11B1
cytochrome P450 family 11 subfamily B member 1
[4]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing syndrome
[4]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing synd
...
Metyrapone
Metyrapone
💬
2. CYP11B1
×
Name
Other Names
Metyrapone
Metyrapone (JP18/USP/INN)
Metopirone (TN)
Metyrapone
[1]
75
75
💬
2. CYP11B1
×
Disease ID
Name
75
Cushing disease
3
CYP11B1
💬
3. CYP11B1
×
Name
Full Name
CYP11B1
cytochrome P450 family 11 subfamily B member 1
[4]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing syndrome
[4]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing synd
...
Levoketoconazole
Levoketoconazole
💬
3. CYP11B1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
Levoketoconazole
[1]
75
75
💬
3. CYP11B1
×
Disease ID
Name
75
Cushing disease
4
CYP17A1
💬
4. CYP17A1
×
Name
Full Name
CYP17A1
cytochrome P450 family 17 subfamily A member 1
[6]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling pathway
,
Cortisol synthesis and secretion
,
Cushing syndrome
[6]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling p
...
Ketoconazole
Ketoconazole
💬
4. CYP17A1
×
Name
Other Names
Ketoconazole
Ketoconazole (JP18/USP)
Nizoral (TN)
Xolegel (TN)
Ketoconazole
[3]
8
8
,
13
,
75
💬
4. CYP17A1
×
Disease ID
Name
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
75
Cushing disease
5
CYP17A1
💬
5. CYP17A1
×
Name
Full Name
CYP17A1
cytochrome P450 family 17 subfamily A member 1
[6]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling pathway
,
Cortisol synthesis and secretion
,
Cushing syndrome
[6]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling p
...
Levoketoconazole
Levoketoconazole
💬
5. CYP17A1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
Levoketoconazole
[1]
75
75
💬
5. CYP17A1
×
Disease ID
Name
75
Cushing disease
6
AGTR1
💬
6. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Angiotensin II
Angiotensin II
💬
6. AGTR1
×
Name
Other Names
Angiotensin II
Angiotensin II (INN)
Angiotensin II
[7]
17
17
,
19
,
46
,
66
,
86
,
222
,
224
💬
6. AGTR1
×
Disease ID
Name
17
Multiple system atrophy
19
Lysosomal storage disease
46
Malignant rheumatoid arthritis
66
IgA nephropathy
86
Pulmonary arterial hypertension
222
Primary nephrotic syndrome
224
Purpura nephritis
7
AGTR1
💬
7. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Valsartan
Valsartan
💬
7. AGTR1
×
Name
Other Names
Valsartan
Valsartan (JP18/USP/INN)
Diovan (TN)
Valsartan
[7]
57
57
,
58
,
66
,
75
,
218
,
222
,
224
💬
7. AGTR1
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
58
Hypertrophic cardiomyopathy
66
IgA nephropathy
75
Cushing disease
218
Alport syndrome
222
Primary nephrotic syndrome
224
Purpura nephritis
8
AGTR1
💬
8. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Candesartan
Candesartan
💬
8. AGTR1
×
Name
Other Names
Candesartan
Candesartan (USAN/INN)
Candesartan
[2]
58
58
,
67
💬
8. AGTR1
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
67
Polycystic kidney disease
9
AGTR1
💬
9. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Irbesartan
Irbesartan
💬
9. AGTR1
×
Name
Other Names
Irbesartan
Irbesartan (JP18/USP/INN)
Avapro (TN)
Irbesartan
[4]
66
66
,
167
,
168
,
222
💬
9. AGTR1
×
Disease ID
Name
66
IgA nephropathy
167
Marfan syndrome
168
Ehlers-Danlos syndrome
222
Primary nephrotic syndrome
10
AGTR1
💬
10. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Candesartan cilexetil
Candesartan cilexetil
💬
10. AGTR1
×
Name
Other Names
Candesartan cilexetil
Candesartan cilexetil (JP18/USP)
Atacand (TN)
CANDESARTAN
Candesartan cilexetil
[1]
67
67
💬
10. AGTR1
×
Disease ID
Name
67
Polycystic kidney disease