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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
IFNG
31件:
Proteasome
Proteasome
,
Cytokine-cytokine receptor interaction
,
HIF-1 signaling pathway
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Type I diabetes mellitus
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Influenza A
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Fluid shear stress and atherosclerosis
31件:
Proteasome
,
Cytokine-cytokine receptor interaction
,
HIF-1 signaling pathway
,
Necroptosis
,
TGF-b
...
D04242
D04242
Fontolizumab
1件:
46
46
2
IFNG
31件:
Proteasome
Proteasome
,
Cytokine-cytokine receptor interaction
,
HIF-1 signaling pathway
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Type I diabetes mellitus
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Influenza A
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Fluid shear stress and atherosclerosis
31件:
Proteasome
,
Cytokine-cytokine receptor interaction
,
HIF-1 signaling pathway
,
Necroptosis
,
TGF-b
...
D11120
D11120
Emapalumab
3件:
49
49
,
65
,
107
3
IL4
16件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Leishmaniasis
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
16件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
D03117
D03117
Binetrakin
1件:
46
46
4
IL5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
D04923
D04923
Mepolizumab
4件:
44
44
,
45
,
98
,
162
5
IL5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
D08985
D08985
Reslizumab
2件:
44
44
,
98
6
IL10
21件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
FoxO signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
T cell receptor signaling pathway
,
Intestinal immune network for IgA production
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Staphylococcus aureus infection
,
Tuberculosis
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Allograft rejection
21件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
D01583
D01583
Pirfenidone
11件:
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
7
IL12A
23件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Type I diabetes mellitus
,
Pertussis
,
Legionellosis
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Inflammatory bowel disease
,
Allograft rejection
,
Lipid and atherosclerosis
23件:
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like recept
...
D09214
D09214
Ustekinumab
16件:
37
37
,
40
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
93
,
96
,
97
,
160
,
162
,
269
,
271
8
IL12B
23件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Type I diabetes mellitus
,
Pertussis
,
Legionellosis
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
Inflammatory bowel disease
,
Allograft rejection
,
Lipid and atherosclerosis
23件:
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like recept
...
D09214
D09214
Ustekinumab
16件:
37
37
,
40
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
93
,
96
,
97
,
160
,
162
,
269
,
271
9
TNF
63件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Apoptosis
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Asthma
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Dilated cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
63件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral pr
...
D00742
D00742
Etanercept
16件:
15
15
,
28
,
35
,
38
,
39
,
46
,
50
,
53
,
56
,
60
,
85
,
107
,
228
,
270
,
271
,
285
10
TNF
63件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Apoptosis
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Asthma
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Dilated cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
63件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral pr
...
D00754
D00754
Thalidomide
20件:
2
2
,
16
,
20
,
28
,
49
,
51
,
53
,
56
,
65
,
84
,
85
,
94
,
96
,
97
,
227
,
271
,
280
,
298
,
300
,
331