Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D09916	Ivacaftor	1件: 299
2	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D10134	Lumacaftor	1件: 299
3	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D11041	Tezacaftor	1件: 299
4	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D11423	Deutivacaftor	1件: 299
5	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D11507	Elexacaftor	1件: 299
6	CFTR	6件: cAMP signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secre ...	D11724	Galicaftor	1件: 299
7	HMGCR	3件: Terpenoid backbone biosynthesis, Metabolic pathways, Bile secretion	D00359	Lovastatin	11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
8	HMGCR	3件: Terpenoid backbone biosynthesis, Metabolic pathways, Bile secretion	D00434	Simvastatin	21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
9	HMGCR	3件: Terpenoid backbone biosynthesis, Metabolic pathways, Bile secretion	D07474	Atorvastatin	19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
10	HMGCR	3件: Terpenoid backbone biosynthesis, Metabolic pathways, Bile secretion	D07983	Fluvastatin	3件: 79, 218, 222

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