Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CDK4	8件: p53 signaling pathway, PI3K-Akt signaling pathway, Tight junction, T cell receptor signaling pat ...	D10688	Abemaciclib	1件: 34
2	CDK6	6件: p53 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Viral carcinogenesis, Pan ...	D10688	Abemaciclib	1件: 34
3	BCL2	14件: Platinum drug resistance, Sphingolipid signaling pathway, p53 signaling pathway, Protein proces ...	D10679	Venetoclax	1件: 28
4	RRM2	3件: Purine metabolism, Pyrimidine metabolism, p53 signaling pathway	D00341	Hydroxyurea	8件: 3, 13, 19, 20, 65, 85, 86, 284
5	CASP9	16件: Platinum drug resistance, p53 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pat ...	D11195	Rimiducid	6件: 19, 60, 65, 284, 285, 326

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