Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	FCER1A	4件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...	D05251	Omalizumab	7件: 46, 53, 65, 98, 162, 226, 299
2	IL4	15件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03117	Binetrakin	1件: 46
3	IL5	12件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...	D04923	Mepolizumab	4件: 44, 45, 98, 162
4	IL5	12件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...	D08985	Reslizumab	2件: 44, 98
5	IL10	19件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...	D01583	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
6	IL13	8件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...	D08857	Anrukinzumab	1件: 97
7	IL13	8件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...	D09633	Lebrikizumab	1件: 85
8	IL13	8件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...	D09979	Tralokinumab	2件: 85, 97
9	TNF	56件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with ...	D00742	Etanercept	16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
10	TNF	56件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with ...	D00754	Thalidomide	20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331

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