Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	PDE10A	[3] Purine metabolism, Metabolic pathways, Morphine addiction	D00227	Aminophylline	[1] 63
2	PDE10A	[3] Purine metabolism, Metabolic pathways, Morphine addiction	D00371	Theophylline	[2] 236, 299
3	PDE10A	[3] Purine metabolism, Metabolic pathways, Morphine addiction	D06103	Theophylline	[2] 236, 299
4	PDE10A	[3] Purine metabolism, Metabolic pathways, Morphine addiction	D07546	Bucladesine	[1] 246
5	PDE10A	[3] Purine metabolism, Metabolic pathways, Morphine addiction	D07961	Flavoxate	[1] 226
6	CA5B	[2] Nitrogen metabolism, Metabolic pathways	D00218	Acetazolamide	[8] 13, 86, 90, 115, 154, 155, 225, 230
7	CA5B	[2] Nitrogen metabolism, Metabolic pathways	D00518	Diclofenamide	[1] 114
8	CA5B	[2] Nitrogen metabolism, Metabolic pathways	D07871	Dorzolamide	[1] 90
9	TPH2	[3] Tryptophan metabolism, Metabolic pathways, Serotonergic synapse	D09973	Telotristat	[1] 97
10	ADH1A	[5] Tyrosine metabolism, Pyruvate metabolism, Retinol metabolism, Metabolism of xenobiotics by cytoc ...	D00707	Fomepizole	[1] 301

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