Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[2] Nitrogen metabolism, Metabolic pathways

Acetazolamide 💬

[8] 13, 86, 90, 115, 154, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
155	Acquired aphasia with convulsive disorder
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome

2

[2] Nitrogen metabolism, Metabolic pathways

Dorzolamide 💬

[1] 90 💬

3

[2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

Brimonidine 💬

[2] 13, 90 💬

4

[2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

Brimonidine 💬

[2] 13, 90 💬

5

[2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

Brimonidine 💬

[2] 13, 90 💬

6

[9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...

[7] 6, 13, 17, 90, 140, 164, 201 💬

7

[10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap ...

[6] 6, 17, 90, 140, 164, 201 💬

8

[8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap jun ...

[6] 6, 17, 90, 140, 164, 201 💬

9

[2] Neuroactive ligand-receptor interaction, Dopaminergic synapse

[6] 6, 17, 90, 140, 164, 201 💬

10

[2] Neuroactive ligand-receptor interaction, Dopaminergic synapse

[6] 6, 17, 90, 140, 164, 201 💬

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