Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D07945	Fenfluramine	4件: 140, 144, 145, 149
2	CYP46A1	1件: Primary bile acid biosynthesis	D11590	Soticlestat	2件: 140, 144
3	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D10915	Cannabidiol	20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
4	CNR2	1件: Neuroactive ligand-receptor interaction	D10915	Cannabidiol	10件: 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
5	DDC	9件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...	D00558	Carbidopa	7件: 6, 13, 17, 90, 140, 164, 201
6	DRD1	10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
7	DRD2	8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap jun ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
8	DRD3	2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
9	DRD4	2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
10	DRD5	4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopa ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201

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