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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CD52
-
D02802
D02802
Alemtuzumab
21件:
15
15
,
19
,
20
,
36
,
43
,
44
,
46
,
49
,
51
,
60
,
62
,
63
,
65
,
85
,
96
,
164
,
234
,
283
,
284
,
285
,
326
2
MTOR
51件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1 signaling pathway
,
Phospholipase D signaling pathway
,
Autophagy - other
,
Autophagy - animal
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Cellular senescence
,
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
JAK-STAT signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Insulin signaling pathway
,
Thyroid hormone signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Growth hormone synthesis, secretion and action
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Pathways of neurodegeneration - multiple diseases
,
Shigellosis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Colorectal cancer
,
Pancreatic cancer
,
Glioma
,
Prostate cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
51件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1
...
D00753
D00753
Sirolimus
40件:
2
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
,
98
,
137
,
157
,
158
,
192
,
193
,
222
,
256
,
277
,
278
,
279
,
280
,
281
,
283
,
300
,
331
40件:
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
, ...
3
HMGCR
4件:
Terpenoid backbone biosynthesis
Terpenoid backbone biosynthesis
,
Metabolic pathways
,
AMPK signaling pathway
,
Bile secretion
D00434
D00434
Simvastatin
21件:
6
6
,
13
,
15
,
34
,
46
,
49
,
51
,
66
,
79
,
86
,
89
,
94
,
158
,
160
,
162
,
195
,
265
,
288
,
298
,
299
,
310
4
IL1R1
13件:
MAPK signaling pathway
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Inflammatory mediator regulation of TRP channels
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Amoebiasis
,
Human cytomegalovirus infection
,
Human T-cell leukemia virus 1 infection
,
Fluid shear stress and atherosclerosis
13件:
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
O
...
D02934
D02934
Anakinra
18件:
2
2
,
13
,
15
,
28
,
37
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
86
,
97
,
106
,
107
,
266
,
299
5
ITGA4
14件:
PI3K-Akt signaling pathway
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
,
Hematopoietic cell lineage
,
Leukocyte transendothelial migration
,
Intestinal immune network for IgA production
,
Regulation of actin cytoskeleton
,
Yersinia infection
,
Leishmaniasis
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
Arrhythmogenic right ventricular cardiomyopathy
,
Dilated cardiomyopathy
14件:
PI3K-Akt signaling pathway
,
Focal adhesion
,
ECM-receptor interaction
,
Cell adhesion molecules
, ...
D06886
D06886
Natalizumab
6件:
13
13
,
15
,
25
,
46
,
63
,
96
6
LTA
7件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
TNF signaling pathway
,
Type I diabetes mellitus
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
7件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine rec
...
D00742
D00742
Etanercept
16件:
15
15
,
28
,
35
,
38
,
39
,
46
,
50
,
53
,
56
,
60
,
85
,
107
,
228
,
270
,
271
,
285
7
PPARG
11件:
PPAR signaling pathway
PPAR signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Osteoclast differentiation
,
Thermogenesis
,
Non-alcoholic fatty liver disease
,
Huntington disease
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Thyroid cancer
,
Lipid and atherosclerosis
11件:
PPAR signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Osteoclast differ
...
D08378
D08378
Pioglitazone
17件:
2
2
,
6
,
13
,
15
,
20
,
46
,
49
,
65
,
67
,
78
,
81
,
86
,
96
,
229
,
265
,
298
,
299
8
SNAP25
2件:
Synaptic vesicle cycle
Synaptic vesicle cycle
,
Insulin secretion
D00783
D00783
Botulinum toxin type A
14件:
2
2
,
5
,
6
,
7
,
13
,
15
,
17
,
36
,
47
,
51
,
70
,
113
,
149
,
226
9
TNF
67件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Apoptosis
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Asthma
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Dilated cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
67件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral pr
...
D00742
D00742
Etanercept
16件:
15
15
,
28
,
35
,
38
,
39
,
46
,
50
,
53
,
56
,
60
,
85
,
107
,
228
,
270
,
271
,
285
10
IL1R2
7件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
Amoebiasis
,
Human T-cell leukemia virus 1 infection
,
Transcriptional misregulation in cancer
,
Prostate cancer
,
Fluid shear stress and atherosclerosis
7件:
Cytokine-cytokine receptor interaction
,
Hematopoietic cell lineage
,
Amoebiasis
,
Human T-cell leu
...
D02934
D02934
Anakinra
18件:
2
2
,
13
,
15
,
28
,
37
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
86
,
97
,
106
,
107
,
266
,
299