Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	EPHA2	[5] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathwa ...	D03658	Dasatinib	[2] 51, 85
2	EPHA2	[5] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathwa ...	D06414	Dasatinib	[2] 51, 85
3	EPHB4	[1] Axon guidance	D11772	Tesevatinib	[1] 67
4	FYN	[13] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, Osteoclast di ...	D03658	Dasatinib	[2] 51, 85
5	FYN	[13] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, Osteoclast di ...	D06414	Dasatinib	[2] 51, 85
6	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D03252	Bosutinib	[2] 2, 67
7	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D03658	Dasatinib	[2] 51, 85
8	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D06414	Dasatinib	[2] 51, 85
9	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D08066	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
10	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D08953	Nilotinib	[5] 6, 8, 34, 51, 86

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