Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	MAPK14	[34] MAPK signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, ...	D09639	Losmapimod	[2] 113, 222
2	MAPK14	[34] MAPK signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, ...	D10959	Neflamapimod	[1] 8
3	CSF1R	[8] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction ...	D08552	Sunitinib	[2] 28, 34
4	CSF1R	[8] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction ...	D11270	Pexidartinib	[1] 34
5	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D01977	Gefitinib	[1] 75
6	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D03455	Cetuximab	[2] 51, 86
7	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D07907	Erlotinib	[1] 94
8	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D08108	Lapatinib	[3] 34, 74, 75
9	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D08950	Neratinib	[1] 34
10	EGFR	[18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signalin ...	D11251	Icotinib	[1] 34

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