Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	MAPK14	[9] VEGF signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, ...	D09639	Losmapimod	[2] 113, 222
2	MAPK14	[9] VEGF signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, ...	D10959	Neflamapimod	[1] 8
3	IFNG	[5] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasm ...	D04242	Fontolizumab	[1] 46
4	IFNG	[5] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasm ...	D11120	Emapalumab	[3] 49, 65, 107
5	IFNGR1	[4] Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis	D00747	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326
6	IFNGR2	[4] Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis	D00747	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326
7	IL2RA	[3] Viral protein interaction with cytokine and cytokine receptor, Th1 and Th2 cell differentiation, ...	D00748	Aldesleukin	[6] 2, 35, 49, 65, 96, 97
8	IL2RA	[3] Viral protein interaction with cytokine and cytokine receptor, Th1 and Th2 cell differentiation, ...	D03058	Basiliximab	[6] 2, 50, 66, 97, 222, 228
9	IL2RA	[3] Viral protein interaction with cytokine and cytokine receptor, Th1 and Th2 cell differentiation, ...	D03639	Daclizumab	[8] 13, 56, 60, 65, 97, 107, 283, 284
10	IL2RB	[4] Viral protein interaction with cytokine and cytokine receptor, Th1 and Th2 cell differentiation, ...	D00748	Aldesleukin	[6] 2, 35, 49, 65, 96, 97

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