Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[28] Endocrine resistance, Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular s ...

Abemaciclib 💬

[1] 34 💬

2

[23] Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syn ...

Abemaciclib 💬

[1] 34 💬

3

[43] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Platinum drug resistance, NF-k ...

Venetoclax 💬

[1] 28 💬

4

[7] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzyme ...

Hydroxyurea 💬

[8] 3, 13, 19, 20, 65, 85, 86, 284 💬

Disease ID	Name
3	Spinal muscular atrophy
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
20	Adrenoleukodystrophy
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
284	Diamond-Blackfan anemia

5

[35] Platinum drug resistance, p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Apoptos ...

[6] 19, 60, 65, 284, 285, 326 💬

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