Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CHRNA3	[3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor ...	D03365	Nicotine	[3] 6, 13, 84
2	CHRNA4	[4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carci ...	D03365	Nicotine	[3] 6, 13, 84
3	CHRNA4	[4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carci ...	D08669	Varenicline	[3] 6, 18, 53
4	CHRNA7	[5] Neuroactive ligand-receptor interaction, Cholinergic synapse, Pathways of neurodegeneration - mu ...	D03365	Nicotine	[3] 6, 13, 84
5	CHRNB2	[4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carci ...	D03365	Nicotine	[3] 6, 13, 84
6	CHRNB2	[4] Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carci ...	D08669	Varenicline	[3] 6, 18, 53
7	CHRNB4	[3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor ...	D03365	Nicotine	[3] 6, 13, 84
8	ADRB1	[7] Neuroactive ligand-receptor interaction, Gap junction, Regulation of lipolysis in adipocytes, Re ...	D00076	Norepinephrine	[2] 22, 296
9	ADRB1	[7] Neuroactive ligand-receptor interaction, Gap junction, Regulation of lipolysis in adipocytes, Re ...	D00095	Epinephrine	[3] 46, 70, 96
10	ADRB1	[7] Neuroactive ligand-receptor interaction, Gap junction, Regulation of lipolysis in adipocytes, Re ...	D00124	Ephedrine	[1] 11

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