Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CCR5	[7] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Viral protein interaction with ...	D06670	Maraviroc	[2] 46, 84
2	CCR5	[7] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Viral protein interaction with ...	D09878	Cenicriviroc	[1] 94
3	MAPK14	[41] MAPK signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, ...	D09639	Losmapimod	[2] 113, 222
4	MAPK14	[41] MAPK signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, ...	D10959	Neflamapimod	[1] 8
5	MTOR	[26] Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D00753	Sirolimus	[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...
6	MTOR	[26] Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D02714	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277
7	MTOR	[26] Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D06068	Temsirolimus	[1] 13
8	IFNA1	[15] PI3K-Akt signaling pathway, Necroptosis, Toll-like receptor signaling pathway, NOD-like recepto ...	D09662	Rontalizumab	[1] 49
9	IFNA1	[15] PI3K-Akt signaling pathway, Necroptosis, Toll-like receptor signaling pathway, NOD-like recepto ...	D09668	Sifalimumab	[1] 49
10	IFNA2	[15] PI3K-Akt signaling pathway, Necroptosis, Toll-like receptor signaling pathway, NOD-like recepto ...	D09662	Rontalizumab	[1] 49

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