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No.

KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

CA5B 💬

[2] Nitrogen metabolism, Metabolic pathways

Acetazolamide 💬

Acetazolamide

[8] 13, 86, 90, 115, 154, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
155	Acquired aphasia with convulsive disorder
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome

F8 💬

[1] Complement and coagulation cascades

Desmopressin 💬

Desmopressin

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

CA14 💬

[2] Nitrogen metabolism, Metabolic pathways

Acetazolamide 💬

Acetazolamide

[8] 13, 86, 90, 115, 154, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
155	Acquired aphasia with convulsive disorder
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome

GUCY1A2 💬

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...

Riociguat 💬

Riociguat

[6] 51, 84, 86, 88, 225, 299 💬

GUCY1A1 💬

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...

Riociguat 💬

Riociguat

[6] 51, 84, 86, 88, 225, 299 💬

GUCY1B1 💬

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...

Riociguat 💬

Riociguat

[6] 51, 84, 86, 88, 225, 299 💬

HMGCR 💬

[4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion

Atorvastatin 💬

Atorvastatin

[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
58	Hypertrophic cardiomyopathy
63	Idiopathic thrombocytopenic purpura
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
96	Crohn disease
97	Ulcerative colitis
160	Congenital ichthyosis
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
265	Lipodystrophy
271	Ankylosing spondylitis
297	Alagille syndrome
299	Cystic fibrosis

CA13 💬

[2] Nitrogen metabolism, Metabolic pathways

Acetazolamide 💬

Acetazolamide

[8] 13, 86, 90, 115, 154, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
155	Acquired aphasia with convulsive disorder
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome

NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption

Spironolactone 💬

Spironolactone

[8] 46, 58, 67, 86, 113, 210, 218, 225 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
218	Alport syndrome
225	Congenital nephrogenic diabetes insipidus

ATP4A 💬

[4] Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secr ...

Omeprazole 💬

Omeprazole

[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
225	Congenital nephrogenic diabetes insipidus
271	Ankylosing spondylitis
282	Congenital dyserythropoietic anemia
294	Congenital diaphragmatic hernia
298	Hereditary pancreatitis
299	Cystic fibrosis

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