Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[28] Endocrine resistance, Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular s ...

Abemaciclib 💬

[1] 34 💬

2

[23] Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syn ...

Abemaciclib 💬

[1] 34 💬

3

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

[2] 2, 67 💬

4

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

[2] 51, 85 💬

5

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

[2] 51, 85 💬

6

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
87	Pulmonary veno-occlusive disease
88	Chronic thromboembolic pulmonary hypertension
89	Lymphangioleiomyomatosis
162	Pemphigoid

7

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

[5] 6, 8, 34, 51, 86 💬

8

[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...

Saracatinib 💬

[3] 6, 89, 272 💬

9

[15] Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, Neutrophi ...

Vorinostat 💬

[2] 75, 96 💬

10

[15] Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, Neutrophi ...

Vorinostat 💬

[2] 75, 96 💬

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