Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MET	2件: Transcriptional misregulation in cancer, Renal cell carcinoma	D10062	Cabozantinib	1件: 34
2	PIK3CA	15件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D11011	Alpelisib	1件: 138
3	PIK3CA	15件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D11158	Leniolisib	2件: 53, 65
4	PIK3CB	15件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D11158	Leniolisib	2件: 53, 65
5	PIK3CD	15件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D11158	Leniolisib	2件: 53, 65
6	PIK3CD	15件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripote ...	D11437	Parsaclisib	3件: 35, 53, 61
7	MAP2K1	13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Sig ...	D09666	Selumetinib	1件: 34
8	MAP2K1	13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Sig ...	D10175	Trametinib	4件: 2, 34, 279, 280
9	MAP2K1	13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Sig ...	D10405	Cobimetinib	1件: 280
10	MAP2K1	13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Sig ...	D10604	Binimetinib	1件: 34

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