Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MAPK14	21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathw ...	D09639	Losmapimod	2件: 113, 222
2	MAPK14	21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathw ...	D10959	Neflamapimod	1件: 8
3	IGF1R	7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of ste ...	D03297	Mecasermin	6件: 65, 78, 96, 168, 265, 299
4	IGF1R	7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of ste ...	D09680	Teprotumumab	1件: 51
5	IGF1R	7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of ste ...	D09925	Linsitinib	1件: 232
6	PDE3B	4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocyte ...	D00227	Aminophylline	1件: 63
7	PDE3B	4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocyte ...	D00371	Theophylline	2件: 236, 299
8	PDE3B	4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocyte ...	D00417	Milrinone	1件: 294
9	PDE3B	4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocyte ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
10	PDE3B	4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocyte ...	D01385	Ibudilast	2件: 2, 13

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