Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ELANE 2件: Transcriptional misregulation in cancer, Systemic lupus erythematosus D03788 Sivelestat 3件: 13, 85, 96
2 GRIN2A 1件: Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
3 GRIN2A 1件: Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
4 GRIN2A 1件: Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
5 GRIN2A 1件: Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
6 GRIN2A 1件: Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
7 GRIN2A 1件: Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
8 GRIN2A 1件: Systemic lupus erythematosus D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
9 GRIN2A 1件: Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
10 GRIN2B 1件: Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
11 GRIN2B 1件: Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
12 GRIN2B 1件: Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
13 GRIN2B 1件: Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
14 GRIN2B 1件: Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
15 GRIN2B 1件: Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
16 GRIN2B 1件: Systemic lupus erythematosus D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
17 GRIN2B 1件: Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
18 IFNG 8件: TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04242 Fontolizumab 1件: 46
19 IFNG 8件: TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D11120 Emapalumab 3件: 49, 65, 107
20 IL10 6件: Viral protein interaction with cytokine and cytokine receptor, T cell receptor signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
21 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00742 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
22 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
23 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
24 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02597 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
25 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
26 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
27 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
28 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
29 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D05393 Pegsunercept 1件: 46
30 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D08976 Pomalidomide 5件: 28, 51, 85, 227, 331
31 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D09944 Ozoralizumab 1件: 46
32 C1R 1件: Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
33 C1S 1件: Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
34 C1S 1件: Systemic lupus erythematosus D11530 Sutimlimab 1件: 61
35 C3 3件: Tuberculosis, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan 4件: 2, 61, 62, 222
36 C5 1件: Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
37 C5 1件: Systemic lupus erythematosus D11054 Ravulizumab 7件: 2, 11, 13, 50, 62, 66, 109
38 C5 1件: Systemic lupus erythematosus D11473 Nomacopan 3件: 62, 109, 162
39 C5 1件: Systemic lupus erythematosus D11477 Pozelimab 2件: 11, 62
40 C5 1件: Systemic lupus erythematosus D11696 Crovalimab 2件: 62, 109
41 C5 1件: Systemic lupus erythematosus D11838 Vilobelimab 3件: 43, 44, 269
42 C5 1件: Systemic lupus erythematosus D12357 Zilucoplan 3件: 2, 11, 62
43 CD80 5件: Virion - Adenovirus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
44 CD80 5件: Virion - Adenovirus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept 1件: 46
45 CD86 6件: Virion - Adenovirus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
46 CD86 6件: Virion - Adenovirus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept 1件: 46
47 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11357 Bleselumab 1件: 222
48 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11597 Ravagalimab 2件: 53, 97
49 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11610 Iscalimab 2件: 49, 53
50 CD40LG 4件: T cell receptor signaling pathway, Toxoplasmosis, Systemic lupus erythematosus, Viral myocarditis D06193 Toralizumab 1件: 63