Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CYSLTR1	[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction	D01385	Ibudilast	[2] 2, 13
2	CYSLTR1	[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction	D06659	Tipelukast	[1] 85
3	CYSLTR1	[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction	D08229	Montelukast	[8] 6, 13, 46, 61, 63, 85, 98, 228
4	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00113	Atropine	[2] 2, 299
5	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00138	Scopolamine	[1] 2
6	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00270	Chlorpromazine	[1] 254
7	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00397	Tropicamide	[1] 6
8	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D00465	Oxybutynin	[3] 6, 13, 53
9	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D08441	Propiverine	[1] 226
10	CHRM1	[7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D08638	Trihexyphenidyl	[2] 5, 6

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