Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ADH1A	[9] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	[1] 301
2	ADH1B	[9] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	[1] 301
3	CPT1C	[7] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, T ...	D08340	Perhexiline	[2] 58, 272
4	ADH1C	[9] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	[1] 301
5	CPT1A	[8] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, T ...	D08340	Perhexiline	[2] 58, 272
6	CPT1B	[9] Fatty acid degradation, Fatty acid metabolism, PPAR signaling pathway, AMPK signaling pathway, T ...	D08340	Perhexiline	[2] 58, 272
7	MAPK14	[60] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D09639	Losmapimod	[2] 113, 222
8	MAPK14	[60] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D10959	Neflamapimod	[1] 8
9	IL17RA	[3] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Alcoholic liver disease	D10061	Brodalumab	[2] 37, 51
10	IFNA1	[25] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Toll-like rece ...	D09662	Rontalizumab	[1] 49

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