DDrare
Disease
Drug
Target Gene/Pathway
Contact
JA
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 40 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
TUBB3
💬
1. TUBB3
×
Name
Full Name
TUBB3
tubulin beta 3 class III
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
1. TUBB3
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
Colchicine
[7]
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
1. TUBB3
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
42
Polyarteritis nodosa
46
Malignant rheumatoid arthritis
56
Behcet disease
93
Primary biliary cholangitis
210
Single Ventricle
266
Familial mediterranean fever
2
TUBB4A
💬
2. TUBB4A
×
Name
Full Name
TUBB4A
tubulin beta 4A class IVa
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
2. TUBB4A
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
Colchicine
[7]
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
2. TUBB4A
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
42
Polyarteritis nodosa
46
Malignant rheumatoid arthritis
56
Behcet disease
93
Primary biliary cholangitis
210
Single Ventricle
266
Familial mediterranean fever
3
TUBB4B
💬
3. TUBB4B
×
Name
Full Name
TUBB4B
tubulin beta 4B class IVb
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Colchicine
Colchicine
💬
3. TUBB4B
×
Name
Other Names
Colchicine
Colchicine (JP18/USP)
Colchicine (TN)
COLCRYS
GLOPERBA
MITIGARE
Colchicine
[7]
2
2
,
42
,
46
,
56
,
93
,
210
,
266
💬
3. TUBB4B
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
42
Polyarteritis nodosa
46
Malignant rheumatoid arthritis
56
Behcet disease
93
Primary biliary cholangitis
210
Single Ventricle
266
Familial mediterranean fever
4
ADRA1D
💬
4. ADRA1D
×
Name
Full Name
ADRA1D
adrenoceptor alpha 1D
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Carvedilol
Carvedilol
💬
4. ADRA1D
×
Name
Other Names
Carvedilol
Carvedilol (JP18/USP/INN)
Artist (TN)
Coreg (TN)
Carvedilol
[4]
57
57
,
86
,
113
,
210
💬
4. ADRA1D
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
86
Pulmonary arterial hypertension
113
Muscular dystrophy
210
Single Ventricle
5
ADRA1B
💬
5. ADRA1B
×
Name
Full Name
ADRA1B
adrenoceptor alpha 1B
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Carvedilol
Carvedilol
💬
5. ADRA1B
×
Name
Other Names
Carvedilol
Carvedilol (JP18/USP/INN)
Artist (TN)
Coreg (TN)
Carvedilol
[4]
57
57
,
86
,
113
,
210
💬
5. ADRA1B
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
86
Pulmonary arterial hypertension
113
Muscular dystrophy
210
Single Ventricle
6
ADRA1A
💬
6. ADRA1A
×
Name
Full Name
ADRA1A
adrenoceptor alpha 1A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[7]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Carvedilol
Carvedilol
💬
6. ADRA1A
×
Name
Other Names
Carvedilol
Carvedilol (JP18/USP/INN)
Artist (TN)
Coreg (TN)
Carvedilol
[4]
57
57
,
86
,
113
,
210
💬
6. ADRA1A
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
86
Pulmonary arterial hypertension
113
Muscular dystrophy
210
Single Ventricle
7
ADRB1
💬
7. ADRB1
×
Name
Full Name
ADRB1
adrenoceptor beta 1
[11]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Gap junction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
[11]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive liga
...
Carvedilol
Carvedilol
💬
7. ADRB1
×
Name
Other Names
Carvedilol
Carvedilol (JP18/USP/INN)
Artist (TN)
Coreg (TN)
Carvedilol
[4]
57
57
,
86
,
113
,
210
💬
7. ADRB1
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
86
Pulmonary arterial hypertension
113
Muscular dystrophy
210
Single Ventricle
8
ADRB2
💬
8. ADRB2
×
Name
Full Name
ADRB2
adrenoceptor beta 2
[9]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
[9]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
Carvedilol
Carvedilol
💬
8. ADRB2
×
Name
Other Names
Carvedilol
Carvedilol (JP18/USP/INN)
Artist (TN)
Coreg (TN)
Carvedilol
[4]
57
57
,
86
,
113
,
210
💬
8. ADRB2
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
86
Pulmonary arterial hypertension
113
Muscular dystrophy
210
Single Ventricle
9
ACE
💬
9. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
[6]
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
[6]
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Enalapril
Enalapril
💬
9. ACE
×
Name
Other Names
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril
[6]
19
19
,
46
,
66
,
113
,
210
,
222
💬
9. ACE
×
Disease ID
Name
19
Lysosomal storage disease
46
Malignant rheumatoid arthritis
66
IgA nephropathy
113
Muscular dystrophy
210
Single Ventricle
222
Primary nephrotic syndrome
10
EDNRA
💬
10. EDNRA
×
Name
Full Name
EDNRA
endothelin receptor type A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Vascular smooth muscle contraction
,
Renin secretion
,
Pathways in cancer
[7]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
Bosentan
Bosentan
💬
10. EDNRA
×
Name
Other Names
Bosentan
Bosentan (USAN)
Bosentan hydrate (JAN)
Tracleer (TN)
Bosentan
[10]
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
10. EDNRA
×
Disease ID
Name
41
Giant cell arteritis
47
Buerger disease
51
Scleroderma
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
211
Hypoplastic left heart syndrome
212
Tricuspid atresia