Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CSF1R 2件: Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D08552 Sunitinib 2件: 28, 34
2 CSF1R 2件: Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D11270 Pexidartinib 1件: 34
3 CSF2 1件: Transcriptional misregulation in cancer D11343 Otilimab 1件: 46
4 ELANE 1件: Transcriptional misregulation in cancer D03788 Sivelestat 3件: 13, 85, 96
5 FLT1 1件: Transcriptional misregulation in cancer D03218 Axitinib 1件: 34
6 FLT1 1件: Transcriptional misregulation in cancer D08552 Sunitinib 2件: 28, 34
7 FLT1 1件: Transcriptional misregulation in cancer D08881 Cediranib 1件: 34
8 FLT1 1件: Transcriptional misregulation in cancer D10481 Nintedanib 5件: 51, 85, 89, 227, 228
9 FLT3 1件: Transcriptional misregulation in cancer D08524 Sorafenib 2件: 34, 86
10 FLT3 1件: Transcriptional misregulation in cancer D08552 Sunitinib 2件: 28, 34
11 FLT3 1件: Transcriptional misregulation in cancer D11270 Pexidartinib 1件: 34
12 GRIA3 1件: Transcriptional misregulation in cancer D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
13 GRIA3 1件: Transcriptional misregulation in cancer D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
14 GRIA3 1件: Transcriptional misregulation in cancer D02696 Talampanel 2件: 2, 6
15 GRIA3 1件: Transcriptional misregulation in cancer D08964 Perampanel 3件: 2, 6, 144
16 HDAC1 2件: Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat 2件: 75, 96
17 HDAC2 2件: Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat 2件: 75, 96
18 IGF1R 1件: Transcriptional misregulation in cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
19 IGF1R 1件: Transcriptional misregulation in cancer D09680 Teprotumumab 1件: 51
20 IGF1R 1件: Transcriptional misregulation in cancer D09925 Linsitinib 1件: 232
21 IL2RB 2件: Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
22 IL6 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
23 IL6 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D08976 Pomalidomide 5件: 28, 51, 85, 227, 331
24 IL6 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D09669 Siltuximab 2件: 28, 331
25 IL6 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D10080 Sirukumab 2件: 41, 46
26 IL6 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D12487 Olokizumab 2件: 46, 96
27 ITGB7 1件: Transcriptional misregulation in cancer D08083 Vedolizumab 3件: 94, 96, 97
28 ITGB7 1件: Transcriptional misregulation in cancer D09901 Etrolizumab 2件: 96, 97
29 ITGB7 1件: Transcriptional misregulation in cancer D10540 Abrilumab 2件: 96, 97
30 MET 1件: Transcriptional misregulation in cancer D10062 Cabozantinib 1件: 34
31 MPO 1件: Transcriptional misregulation in cancer D11684 Verdiperstat 3件: 2, 17, 127
32 NFKB1 4件: Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D01146 Iguratimod 5件: 46, 51, 53, 271, 300
33 NGFR 2件: Virion - Lyssavirus, Transcriptional misregulation in cancer D11028 Cenegermin 2件: 53, 90
34 PML 2件: Ubiquitin mediated proteolysis, Transcriptional misregulation in cancer D00094 Tretinoin 6件: 2, 62, 63, 75, 94, 231
35 PPARG 1件: Transcriptional misregulation in cancer D08378 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
36 PPARG 1件: Transcriptional misregulation in cancer D08491 Rosiglitazone 5件: 46, 75, 97, 222, 265
37 PPARG 1件: Transcriptional misregulation in cancer D11256 Seladelpar 2件: 93, 94
38 PPARG 1件: Transcriptional misregulation in cancer D11603 Leriglitazone 1件: 20
39 PPARG 1件: Transcriptional misregulation in cancer D12242 Bocidelpar 1件: 113
40 RARA 1件: Transcriptional misregulation in cancer D00094 Tretinoin 6件: 2, 62, 63, 75, 94, 231
41 RARA 1件: Transcriptional misregulation in cancer D00348 Isotretinoin 4件: 36, 39, 159, 160
42 RARA 1件: Transcriptional misregulation in cancer D01418 Tamibarotene 2件: 26, 96
43 RARA 1件: Transcriptional misregulation in cancer D02754 Acitretin 1件: 37
44 RARA 1件: Transcriptional misregulation in cancer D02815 Alitretinoin 1件: 49
45 RARA 1件: Transcriptional misregulation in cancer D04162 Fenretinide 1件: 299
46 RARA 1件: Transcriptional misregulation in cancer D06543 Vitamin A 3件: 13, 53, 90
47 RELA 4件: Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D12181 Edasalonexent 1件: 113
48 RXRA 1件: Transcriptional misregulation in cancer D02754 Acitretin 1件: 37
49 RXRA 1件: Transcriptional misregulation in cancer D02815 Alitretinoin 1件: 49
50 RXRA 1件: Transcriptional misregulation in cancer D03106 Bexarotene 2件: 13, 75
51 RXRB 1件: Transcriptional misregulation in cancer D02754 Acitretin 1件: 37
52 RXRB 1件: Transcriptional misregulation in cancer D02815 Alitretinoin 1件: 49
53 RXRB 1件: Transcriptional misregulation in cancer D03106 Bexarotene 2件: 13, 75
54 RXRG 1件: Transcriptional misregulation in cancer D02754 Acitretin 1件: 37
55 RXRG 1件: Transcriptional misregulation in cancer D02815 Alitretinoin 1件: 49
56 RXRG 1件: Transcriptional misregulation in cancer D03106 Bexarotene 2件: 13, 75
57 IL1R2 1件: Transcriptional misregulation in cancer D02934 Anakinra 18件: 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
58 CD86 4件: Virion - Adenovirus, Type I diabetes mellitus, Transcriptional misregulation in cancer, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
59 CD86 4件: Virion - Adenovirus, Type I diabetes mellitus, Transcriptional misregulation in cancer, Viral myocarditis D03222 Belatacept 1件: 46
60 CD40 2件: Transcriptional misregulation in cancer, Viral myocarditis D11357 Bleselumab 1件: 222
61 CD40 2件: Transcriptional misregulation in cancer, Viral myocarditis D11597 Ravagalimab 2件: 53, 97
62 CD40 2件: Transcriptional misregulation in cancer, Viral myocarditis D11610 Iscalimab 2件: 49, 53