Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SIGMAR1 [1] Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2 SIGMAR1 [1] Pathways of neurodegeneration - multiple diseases D07945 Fenfluramine [4] 140, 144, 145, 149
3 SIGMAR1 [1] Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
4 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
5 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
6 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
7 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
8 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
9 TUBB3 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
10 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
11 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
12 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
13 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
14 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
15 TUBB4A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
16 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
17 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
18 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
19 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
20 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
21 TUBB4B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
22 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00113 Atropine [2] 2, 299
23 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine [1] 2
24 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
25 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide [1] 6
26 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin [3] 6, 13, 53
27 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
28 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl [2] 5, 6
29 CHRM1 [3] PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
30 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00113 Atropine [2] 2, 299
31 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine [1] 2
32 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
33 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide [1] 6
34 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin [3] 6, 13, 53
35 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00525 Pilocarpine [3] 6, 53, 299
36 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D00646 Tolterodine [2] 17, 53
37 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D03654 Darifenacin [2] 6, 13
38 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D07226 Fesoterodine [1] 6
39 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D07667 Cevimeline [1] 53
40 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
41 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D08522 Solifenacin [3] 6, 13, 53
42 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl [2] 5, 6
43 CHRM3 [4] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
44 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00113 Atropine [2] 2, 299
45 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine [1] 2
46 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
47 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide [1] 6
48 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin [3] 6, 13, 53
49 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
50 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl [2] 5, 6
51 CHRM5 [2] Regulation of actin cytoskeleton, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
52 CHRNA7 [1] Pathways of neurodegeneration - multiple diseases D03365 Nicotine [3] 6, 13, 84
53 MAPK14 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
54 MAPK14 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
55 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
56 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
57 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
58 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
59 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
60 TUBB [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
61 MTOR [12] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D00753 Sirolimus [40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
62 MTOR [12] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
63 MTOR [12] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Proteoglycans in cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D06068 Temsirolimus [1] 13
64 GRIA1 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
65 GRIA1 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
66 GRIA1 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D02696 Talampanel [2] 2, 6
67 GRIA1 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D08964 Perampanel [3] 2, 6, 144
68 GRIA2 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
69 GRIA2 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
70 GRIA2 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D02696 Talampanel [2] 2, 6
71 GRIA2 [3] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D08964 Perampanel [3] 2, 6, 144
72 GRIA3 [4] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Transcriptional misregulation in cancer D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
73 GRIA3 [4] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Transcriptional misregulation in cancer D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
74 GRIA3 [4] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Transcriptional misregulation in cancer D02696 Talampanel [2] 2, 6
75 GRIA3 [4] Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Transcriptional misregulation in cancer D08964 Perampanel [3] 2, 6, 144
76 GRIA4 [2] Retrograde endocannabinoid signaling, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
77 GRIA4 [2] Retrograde endocannabinoid signaling, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
78 GRIA4 [2] Retrograde endocannabinoid signaling, Pathways of neurodegeneration - multiple diseases D02696 Talampanel [2] 2, 6
79 GRIA4 [2] Retrograde endocannabinoid signaling, Pathways of neurodegeneration - multiple diseases D08964 Perampanel [3] 2, 6, 144
80 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
81 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
82 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07058 Acamprosate [2] 6, 206
83 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07283 Esketamine [3] 2, 4, 70
84 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07441 Amantadine [4] 6, 8, 13, 127
85 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
86 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
87 GRIN1 [5] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D09917 Latrepirdine [1] 8
88 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
89 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
90 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
91 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
92 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
93 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
94 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
95 GRIN2A [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
96 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
97 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
98 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
99 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
100 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
101 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
102 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
103 GRIN2B [6] Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
104 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
105 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
106 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07058 Acamprosate [2] 6, 206
107 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07283 Esketamine [3] 2, 4, 70
108 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07441 Amantadine [4] 6, 8, 13, 127
109 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
110 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
111 GRIN2C [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D09917 Latrepirdine [1] 8
112 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
113 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
114 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07058 Acamprosate [2] 6, 206
115 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07283 Esketamine [3] 2, 4, 70
116 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D07441 Amantadine [4] 6, 8, 13, 127
117 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
118 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
119 GRIN2D [3] Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D09917 Latrepirdine [1] 8
120 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
121 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
122 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
123 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
124 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
125 TUBB8 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
126 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
127 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
128 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
129 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
130 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
131 TUBB2B [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
132 IL1A [6] Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pertussis, Tuberculosis, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
133 IL1A [6] Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pertussis, Tuberculosis, Rheumatoid arthritis D06635 Rilonacept [4] 51, 106, 107, 266
134 IL1A [6] Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Pertussis, Tuberculosis, Rheumatoid arthritis D11253 Bermekimab [1] 51
135 IL1B [12] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
136 IL1B [12] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D06635 Rilonacept [4] 51, 106, 107, 266
137 IL1B [12] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
138 IL1B [12] Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Rheumatoid arthritis D09911 Gevokizumab [4] 41, 50, 56, 269
139 IL6 [13] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
140 IL6 [13] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Rheumatoid arthritis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
141 IL6 [13] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Rheumatoid arthritis D09669 Siltuximab [2] 28, 331
142 IL6 [13] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Rheumatoid arthritis D10080 Sirukumab [2] 41, 46
143 IL6 [13] Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, Th17 cell differentiation, TNF signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Pertussis, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer, Rheumatoid arthritis D12487 Olokizumab [2] 46, 96
144 MAPT [1] Pathways of neurodegeneration - multiple diseases D11210 Flortaucipir [3] 5, 7, 127
145 MAPT [1] Pathways of neurodegeneration - multiple diseases D11293 Gosuranemab [1] 5
146 MAPT [1] Pathways of neurodegeneration - multiple diseases D11384 Hydromethylthionine mesylate [1] 127
147 MAP3K5 [8] Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Tight junction, TNF signaling pathway, Thermogenesis, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases D10988 Selonsertib [1] 86
148 NFKB1 [23] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D01146 Iguratimod [5] 46, 51, 53, 271, 300
149 PPP3CA [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
150 PPP3CA [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
151 PPP3CA [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
152 PPP3CA [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
153 PPP3CA [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
154 PPP3CB [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
155 PPP3CB [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
156 PPP3CB [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
157 PPP3CB [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
158 PPP3CB [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
159 PPP3CC [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
160 PPP3CC [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
161 PPP3CC [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
162 PPP3CC [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
163 PPP3CC [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
164 PPP3R1 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
165 PPP3R1 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
166 PPP3R1 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
167 PPP3R1 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
168 PPP3R1 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
169 PPP3R2 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
170 PPP3R2 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
171 PPP3R2 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
172 PPP3R2 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
173 PPP3R2 [10] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
174 PRKCB [15] Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Salivary secretion, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Proteoglycans in cancer D11935 Enzastaurin [1] 168
175 MAPK11 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
176 MAPK11 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
177 MAPK13 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
178 MAPK13 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
179 MAP2K1 [25] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
180 MAP2K1 [25] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
181 MAP2K1 [25] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
182 MAP2K1 [25] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
183 MAP2K1 [25] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
184 MAP2K2 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
185 MAP2K2 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
186 MAP2K2 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
187 MAP2K2 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
188 MAP2K2 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
189 PSEN1 [2] Wnt signaling pathway, Pathways of neurodegeneration - multiple diseases D09010 Tarenflurbil [1] 13
190 PSMB5 [4] Proteasome, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D03150 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
191 PSMB5 [4] Proteasome, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D08880 Carfilzomib [1] 28
192 PSMB5 [4] Proteasome, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D10130 Ixazomib [5] 13, 16, 28, 51, 61
193 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
194 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00118 Naproxen [4] 13, 46, 107, 271
195 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00120 Sulindac [1] 206
196 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
197 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00130 Diflunisal [1] 28
198 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00132 Ketoprofen [1] 46
199 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00141 Indomethacin [3] 225, 271, 298
200 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
201 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00315 Etodolac [1] 46
202 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00330 Flurbiprofen [3] 13, 21, 46
203 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00428 Salsalate [1] 5
204 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
205 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00568 Rofecoxib [1] 46
206 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D00969 Meloxicam [4] 46, 49, 271, 296
207 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D01049 Nimesulide [1] 46
208 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D01183 Tolfenamic acid [1] 5
209 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D01545 Aceclofenac [1] 46
210 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D02709 Valdecoxib [1] 46
211 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D03710 Etoricoxib [2] 46, 271
212 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D03714 Lumiracoxib [1] 46
213 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D03716 Parecoxib [2] 46, 271
214 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D07816 Diclofenac [5] 13, 34, 46, 78, 271
215 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D08104 Ketorolac [2] 70, 226
216 PTGS2 [7] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Small cell lung cancer D08149 Loxoprofen [2] 46, 271
217 RAF1 [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08524 Sorafenib [2] 34, 86
218 BCL2 [11] Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer D10679 Venetoclax [1] 28
219 RELA [23] Ras signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D12181 Edasalonexent [1] 113
220 MAPK12 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09639 Losmapimod [2] 113, 222
221 MAPK12 [26] Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10959 Neflamapimod [1] 8
222 SLC6A3 [2] Synaptic vesicle cycle, Pathways of neurodegeneration - multiple diseases D03215 Armodafinil [3] 6, 13, 84
223 SLC6A3 [2] Synaptic vesicle cycle, Pathways of neurodegeneration - multiple diseases D04999 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
224 SLC6A3 [2] Synaptic vesicle cycle, Pathways of neurodegeneration - multiple diseases D05458 Phentermine [1] 97
225 SLC6A3 [2] Synaptic vesicle cycle, Pathways of neurodegeneration - multiple diseases D07591 Bupropion [5] 8, 18, 21, 96, 171
226 SLC6A3 [2] Synaptic vesicle cycle, Pathways of neurodegeneration - multiple diseases D08130 Lisdexamfetamine [1] 13
227 SNCA [1] Pathways of neurodegeneration - multiple diseases D11420 Prasinezumab [1] 6
228 SOD1 [3] Peroxisome, Prion disease, Pathways of neurodegeneration - multiple diseases D11811 Tofersen [1] 2
229 BRAF [10] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Pathways of neurodegeneration - multiple diseases, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D08524 Sorafenib [2] 34, 86
230 BRAF [10] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Pathways of neurodegeneration - multiple diseases, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10064 Dabrafenib [1] 34
231 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00742 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
232 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
233 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
234 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02597 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
235 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
236 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
237 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
238 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
239 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D05393 Pegsunercept [1] 46
240 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
241 TNF [20] Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D09944 Ozoralizumab [1] 46
242 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
243 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
244 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
245 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
246 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
247 TUBB2A [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
248 CACNA1B [6] Synaptic vesicle cycle, Retrograde endocannabinoid signaling, Serotonergic synapse, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
249 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
250 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
251 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
252 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
253 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
254 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
255 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
256 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
257 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
258 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
259 CACNA1C [8] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
260 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
261 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
262 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
263 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
264 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
265 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
266 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
267 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
268 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
269 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
270 CACNA1D [8] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
271 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
272 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
273 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
274 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
275 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
276 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
277 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
278 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
279 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
280 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
281 CACNA1F [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
282 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
283 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
284 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
285 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
286 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
287 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
288 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
289 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
290 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
291 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
292 CACNA1S [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
293 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
294 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
295 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
296 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
297 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
298 TUBB1 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28
299 CASP9 [11] Platinum drug resistance, PI3K-Akt signaling pathway, VEGF signaling pathway, Thyroid hormone signaling pathway, Prion disease, Pathways of neurodegeneration - multiple diseases, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
300 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00491 Paclitaxel [2] 46, 85
301 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D00570 Colchicine [7] 2, 42, 46, 56, 93, 210, 266
302 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08675 Vinblastine [2] 34, 65
303 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D08679 Vincristine [4] 26, 34, 65, 331
304 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D09587 Brentuximab vedotin [2] 49, 51
305 TUBB6 [4] Phagosome, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection D11595 Belantamab mafodotin [1] 28