Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D00045 Adenosine 3件: 13, 58, 65
2 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D00227 Aminophylline 1件: 63
3 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D00371 Theophylline 2件: 236, 299
4 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D00528 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
5 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D01453 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
6 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D02769 Adenosine phosphate 1件: 46
7 ADORA1 3件: Sphingolipid signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D06103 Theophylline 2件: 236, 299
8 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00076 Norepinephrine 2件: 22, 296
9 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00095 Epinephrine 3件: 46, 70, 96
10 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00124 Ephedrine 1件: 11
11 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00235 Atenolol 1件: 167
12 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00255 Carvedilol 4件: 57, 86, 113, 210
13 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00378 Timolol 2件: 157, 227
14 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00432 Nadolol 1件: 6
15 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D01277 Droxidopa 5件: 5, 6, 17, 169, 170
16 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02342 Bisoprolol 4件: 58, 67, 86, 113
17 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02349 Dipivefrin 1件: 6
18 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02358 Metoprolol 6件: 17, 57, 58, 113, 193, 226
19 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02910 Amiodarone 2件: 28, 127
20 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D03879 Dobutamine 4件: 57, 58, 86, 215
21 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D05127 Nebivolol 4件: 17, 85, 113, 167
22 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D07660 Celiprolol 1件: 168
23 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D07916 Esmolol 1件: 58
24 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08443 Propranolol 6件: 6, 158, 167, 227, 278, 296
25 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08449 Pseudoephedrine 1件: 17
26 ADRB1 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08600 Timolol 2件: 157, 227
27 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00076 Norepinephrine 2件: 22, 296
28 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00095 Epinephrine 3件: 46, 70, 96
29 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00124 Ephedrine 1件: 11
30 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00255 Carvedilol 4件: 57, 86, 113, 210
31 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00378 Timolol 2件: 157, 227
32 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00432 Nadolol 1件: 6
33 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D01277 Droxidopa 5件: 5, 6, 17, 169, 170
34 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02147 Salbutamol 12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
35 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02151 Tulobuterol 1件: 6
36 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02349 Dipivefrin 1件: 6
37 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D05792 Salmeterol 1件: 299
38 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D07713 Clenbuterol 5件: 1, 2, 6, 13, 256
39 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D07990 Formoterol 3件: 85, 228, 299
40 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08092 Isoxsuprine 1件: 13
41 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08124 Levosalbutamol 1件: 49
42 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08443 Propranolol 6件: 6, 158, 167, 227, 278, 296
43 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08449 Pseudoephedrine 1件: 17
44 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08570 Terbutaline 1件: 118
45 ADRB2 3件: Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08600 Timolol 2件: 157, 227
46 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00076 Norepinephrine 2件: 22, 296
47 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00095 Epinephrine 3件: 46, 70, 96
48 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D00124 Ephedrine 1件: 11
49 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D01277 Droxidopa 5件: 5, 6, 17, 169, 170
50 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D02349 Dipivefrin 1件: 6
51 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08443 Propranolol 6件: 6, 158, 167, 227, 278, 296
52 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D08449 Pseudoephedrine 1件: 17
53 ADRB3 4件: Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion D09535 Mirabegron 4件: 6, 13, 53, 226
54 INSR 2件: Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03230 Insulin human 2件: 96, 156
55 INSR 2件: Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03250 Insulin glargine 1件: 299
56 INSR 2件: Regulation of lipolysis in adipocytes, Type II diabetes mellitus D04539 Insulin detemir 1件: 299
57 NPR1 4件: Vascular smooth muscle contraction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion D04051 Erythrityl tetranitrate 1件: 46
58 NPR1 4件: Vascular smooth muscle contraction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion D05147 Nesiritide 2件: 46, 58
59 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D00227 Aminophylline 1件: 63
60 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D00371 Theophylline 2件: 236, 299
61 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D00417 Milrinone 1件: 294
62 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D00528 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
63 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D01385 Ibudilast 2件: 2, 13
64 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D01453 Caffeine 8件: 2, 6, 21, 46, 78, 96, 97, 265
65 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D01896 Cilostazol 3件: 46, 51, 70
66 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D04720 Levosimendan 1件: 2
67 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D06103 Theophylline 2件: 236, 299
68 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D07546 Bucladesine 1件: 246
69 PDE3B 2件: Regulation of lipolysis in adipocytes, Renin secretion D07961 Flavoxate 1件: 226
70 PIK3CA 17件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11011 Alpelisib 1件: 138
71 PIK3CA 17件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
72 PIK3CB 17件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
73 PIK3CD 17件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
74 PIK3CD 17件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
75 PTGER3 1件: Regulation of lipolysis in adipocytes D00419 Misoprostol 3件: 46, 70, 271
76 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
77 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00118 Naproxen 4件: 13, 46, 107, 271
78 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00120 Sulindac 1件: 206
79 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
80 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00132 Ketoprofen 1件: 46
81 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00141 Indomethacin 3件: 225, 271, 298
82 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00217 Acetaminophen 15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
83 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00330 Flurbiprofen 3件: 13, 21, 46
84 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D00428 Salsalate 1件: 5
85 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D01183 Tolfenamic acid 1件: 5
86 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D01545 Aceclofenac 1件: 46
87 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D07816 Diclofenac 5件: 13, 34, 46, 78, 271
88 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D08104 Ketorolac 2件: 70, 226
89 PTGS1 2件: Serotonergic synapse, Regulation of lipolysis in adipocytes D08149 Loxoprofen 2件: 46, 271
90 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
91 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00118 Naproxen 4件: 13, 46, 107, 271
92 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00120 Sulindac 1件: 206
93 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
94 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00130 Diflunisal 1件: 28
95 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00132 Ketoprofen 1件: 46
96 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00141 Indomethacin 3件: 225, 271, 298
97 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00217 Acetaminophen 15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
98 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00315 Etodolac 1件: 46
99 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00330 Flurbiprofen 3件: 13, 21, 46
100 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00428 Salsalate 1件: 5
101 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00567 Celecoxib 10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
102 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00568 Rofecoxib 1件: 46
103 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D00969 Meloxicam 4件: 46, 49, 271, 296
104 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D01049 Nimesulide 1件: 46
105 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D01183 Tolfenamic acid 1件: 5
106 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D01545 Aceclofenac 1件: 46
107 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D02709 Valdecoxib 1件: 46
108 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D03710 Etoricoxib 2件: 46, 271
109 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D03714 Lumiracoxib 1件: 46
110 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D03716 Parecoxib 2件: 46, 271
111 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D07816 Diclofenac 5件: 13, 34, 46, 78, 271
112 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D08104 Ketorolac 2件: 70, 226
113 PTGS2 6件: VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Regulation of lipolysis in adipocytes, Small cell lung cancer D08149 Loxoprofen 2件: 46, 271