Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CDK4 4件: Tight junction, T cell receptor signaling pathway, Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib 1件: 34
2 CDK6 2件: Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib 1件: 34
3 NFKB1 12件: Sphingolipid signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod 5件: 46, 51, 53, 271, 300
4 PIK3CA 11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11011 Alpelisib 1件: 138
5 PIK3CA 11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
6 PIK3CB 11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
7 PIK3CD 11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
8 PIK3CD 11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
9 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00109 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
10 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00118 Naproxen 4件: 13, 46, 107, 271
11 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00120 Sulindac 1件: 206
12 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00126 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299
13 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00130 Diflunisal 1件: 28
14 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00132 Ketoprofen 1件: 46
15 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00141 Indomethacin 3件: 225, 271, 298
16 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00217 Acetaminophen 15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
17 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00315 Etodolac 1件: 46
18 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00330 Flurbiprofen 3件: 13, 21, 46
19 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00428 Salsalate 1件: 5
20 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00567 Celecoxib 10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
21 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00568 Rofecoxib 1件: 46
22 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00969 Meloxicam 4件: 46, 49, 271, 296
23 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01049 Nimesulide 1件: 46
24 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01183 Tolfenamic acid 1件: 5
25 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01545 Aceclofenac 1件: 46
26 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D02709 Valdecoxib 1件: 46
27 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03710 Etoricoxib 2件: 46, 271
28 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03714 Lumiracoxib 1件: 46
29 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03716 Parecoxib 2件: 46, 271
30 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D07816 Diclofenac 5件: 13, 34, 46, 78, 271
31 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D08104 Ketorolac 2件: 70, 226
32 PTGS2 3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D08149 Loxoprofen 2件: 46, 271
33 RARB 1件: Small cell lung cancer D00094 Tretinoin 6件: 2, 62, 63, 75, 94, 231
34 RARB 1件: Small cell lung cancer D00348 Isotretinoin 4件: 36, 39, 159, 160
35 RARB 1件: Small cell lung cancer D02754 Acitretin 1件: 37
36 RARB 1件: Small cell lung cancer D02815 Alitretinoin 1件: 49
37 RARB 1件: Small cell lung cancer D04162 Fenretinide 1件: 299
38 RARB 1件: Small cell lung cancer D06543 Vitamin A 3件: 13, 53, 90
39 BCL2 4件: Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, Small cell lung cancer D10679 Venetoclax 1件: 28
40 RELA 12件: Sphingolipid signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent 1件: 113
41 RXRA 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin 1件: 37
42 RXRA 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin 1件: 49
43 RXRA 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene 2件: 13, 75
44 RXRB 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin 1件: 37
45 RXRB 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin 1件: 49
46 RXRB 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene 2件: 13, 75
47 RXRG 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin 1件: 37
48 RXRG 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin 1件: 49
49 RXRG 5件: Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene 2件: 13, 75
50 CASP9 6件: VEGF signaling pathway, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, Small cell lung cancer, Viral myocarditis D11195 Rimiducid 6件: 19, 60, 65, 284, 285, 326