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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

FCER1A 💬

[4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...

Omalizumab 💬

Omalizumab

[7] 46, 53, 65, 98, 162, 226, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
53	Sjogren syndrome
65	Primary immunodeficiency
98	Eosinophilic gastrointestinal disease
162	Pemphigoid
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

IL4 💬

[16] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...

Binetrakin 💬

Binetrakin

[1] 46 💬

IL5 💬

[13] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...

Mepolizumab 💬

Mepolizumab

[4] 44, 45, 98, 162 💬

IL5 💬

[13] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...

Reslizumab 💬

Reslizumab

[2] 44, 98 💬

IL10 💬

[22] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...

Pirfenidone 💬

Pirfenidone

[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
58	Hypertrophic cardiomyopathy
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
164	Oculocutaneous albinism
222	Primary nephrotic syndrome
228	Bronchiolitis obliterans

IL13 💬

[8] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...

Anrukinzumab 💬

Anrukinzumab

[1] 97 💬

IL13 💬

[8] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...

Lebrikizumab 💬

Lebrikizumab

[1] 85 💬

IL13 💬

[8] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 ...

Tralokinumab 💬

Tralokinumab

[2] 85, 97 💬

TNF 💬

[67] Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...

Etanercept 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

Etanercept

[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬

Disease ID	Name
15	Inclusion body myositis
28	Systemic amyloidosis
35	Pemphigus
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
53	Sjogren syndrome
56	Behcet disease
60	Aplastic anemia
85	Idiopathic interstitial pneumonia
107	Juvenile idiopathic arthritis
228	Bronchiolitis obliterans
270	Chronic recurrent multifocal osteomyelitis
271	Ankylosing spondylitis
285	Fanconi anemia

TNF 💬

[67] Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...

Thalidomide 💬

Thalidomide

[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
16	Crow-Fukase syndrome
20	Adrenoleukodystrophy
28	Systemic amyloidosis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
56	Behcet disease
65	Primary immunodeficiency
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
227	Osler disease
271	Ankylosing spondylitis
280	Huge arteriovenous malformation with cervicofacial or limb lesion
298	Hereditary pancreatitis
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

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