Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
2 MAPK14 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
3 CYP17A1 2件: Steroid hormone biosynthesis, Prolactin signaling pathway D00351 Ketoconazole 3件: 8, 13, 75
4 CYP17A1 2件: Steroid hormone biosynthesis, Prolactin signaling pathway D10950 Levoketoconazole 1件: 75
5 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
6 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D00185 Estriol 2件: 13, 227
7 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D00289 Danazol 5件: 60, 63, 64, 65, 285
8 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D00554 Ethinylestradiol 4件: 13, 46, 49, 299
9 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D00575 Mestranol 2件: 46, 49
10 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D01161 Fulvestrant 2件: 49, 86
11 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D01413 Estradiol valerate 1件: 65
12 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D01986 Estriol 2件: 13, 227
13 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D02367 Desogestrel 1件: 230
14 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D07726 Clomifene 1件: 74
15 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
16 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D08465 Raloxifene 1件: 46
17 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D08559 Tamoxifen 3件: 2, 113, 227
18 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D11513 Estetrol 1件: 53
19 ESR1 3件: Prolactin signaling pathway, Thyroid hormone signaling pathway, Proteoglycans in cancer D11514 Estetrol 1件: 53
20 ESR2 1件: Prolactin signaling pathway D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
21 ESR2 1件: Prolactin signaling pathway D00185 Estriol 2件: 13, 227
22 ESR2 1件: Prolactin signaling pathway D00575 Mestranol 2件: 46, 49
23 ESR2 1件: Prolactin signaling pathway D01161 Fulvestrant 2件: 49, 86
24 ESR2 1件: Prolactin signaling pathway D01413 Estradiol valerate 1件: 65
25 ESR2 1件: Prolactin signaling pathway D01986 Estriol 2件: 13, 227
26 ESR2 1件: Prolactin signaling pathway D07726 Clomifene 1件: 74
27 ESR2 1件: Prolactin signaling pathway D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
28 ESR2 1件: Prolactin signaling pathway D08465 Raloxifene 1件: 46
29 ESR2 1件: Prolactin signaling pathway D08559 Tamoxifen 3件: 2, 113, 227
30 ESR2 1件: Prolactin signaling pathway D11513 Estetrol 1件: 53
31 ESR2 1件: Prolactin signaling pathway D11514 Estetrol 1件: 53
32 JAK2 6件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis D09959 Ruxolitinib 3件: 60, 65, 228
33 JAK2 6件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
34 JAK2 6件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis D10308 Baricitinib 13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
35 JAK2 6件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Prolactin signaling pathway, Toxoplasmosis, Tuberculosis D10653 Peficitinib 1件: 46
36 NFKB1 19件: Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer D01146 Iguratimod 5件: 46, 51, 53, 271, 300
37 PIK3CA 23件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11011 Alpelisib 1件: 138
38 PIK3CA 23件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
39 PIK3CB 23件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
40 PIK3CD 23件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
41 PIK3CD 23件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
42 MAPK11 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
43 MAPK11 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
44 MAPK13 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
45 MAPK13 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
46 MAP2K1 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib 1件: 34
47 MAP2K1 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
48 MAP2K1 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib 1件: 280
49 MAP2K1 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib 1件: 34
50 MAP2K1 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D11675 Mirdametinib 1件: 34
51 MAP2K2 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib 1件: 34
52 MAP2K2 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
53 MAP2K2 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib 1件: 280
54 MAP2K2 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib 1件: 34
55 MAP2K2 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D11675 Mirdametinib 1件: 34
56 PRL 1件: Prolactin signaling pathway D00987 Cabergoline 3件: 6, 74, 75
57 PRL 1件: Prolactin signaling pathway D01348 Terguride 2件: 51, 86
58 PRL 1件: Prolactin signaling pathway D03165 Bromocriptine 2件: 6, 74
59 RAF1 17件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D08524 Sorafenib 2件: 34, 86
60 RELA 19件: Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer D12181 Edasalonexent 1件: 113
61 MAPK12 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
62 MAPK12 20件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
63 SRC 12件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib 2件: 2, 67
64 SRC 12件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib 2件: 51, 85
65 SRC 12件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib 2件: 51, 85
66 SRC 12件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib 3件: 6, 89, 272
67 TNFSF11 2件: Prolactin signaling pathway, Rheumatoid arthritis D03684 Denosumab 8件: 46, 50, 70, 93, 95, 96, 274, 299