Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MTOR 5件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D00753 Sirolimus 40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
2 MTOR 5件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D02714 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
3 MTOR 5件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D06068 Temsirolimus 1件: 13
4 GRIA1 1件: Spinocerebellar ataxia D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
5 GRIA1 1件: Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
6 GRIA1 1件: Spinocerebellar ataxia D02696 Talampanel 2件: 2, 6
7 GRIA1 1件: Spinocerebellar ataxia D08964 Perampanel 3件: 2, 6, 144
8 GRIA2 1件: Spinocerebellar ataxia D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
9 GRIA2 1件: Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
10 GRIA2 1件: Spinocerebellar ataxia D02696 Talampanel 2件: 2, 6
11 GRIA2 1件: Spinocerebellar ataxia D08964 Perampanel 3件: 2, 6, 144
12 GRIA3 2件: Spinocerebellar ataxia, Transcriptional misregulation in cancer D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
13 GRIA3 2件: Spinocerebellar ataxia, Transcriptional misregulation in cancer D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
14 GRIA3 2件: Spinocerebellar ataxia, Transcriptional misregulation in cancer D02696 Talampanel 2件: 2, 6
15 GRIA3 2件: Spinocerebellar ataxia, Transcriptional misregulation in cancer D08964 Perampanel 3件: 2, 6, 144
16 GRIN1 1件: Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
17 GRIN1 1件: Spinocerebellar ataxia D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
18 GRIN1 1件: Spinocerebellar ataxia D07058 Acamprosate 2件: 6, 206
19 GRIN1 1件: Spinocerebellar ataxia D07283 Esketamine 3件: 2, 4, 70
20 GRIN1 1件: Spinocerebellar ataxia D07441 Amantadine 4件: 6, 8, 13, 127
21 GRIN1 1件: Spinocerebellar ataxia D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
22 GRIN1 1件: Spinocerebellar ataxia D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
23 GRIN1 1件: Spinocerebellar ataxia D09917 Latrepirdine 1件: 8
24 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
25 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
26 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
27 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
28 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
29 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
30 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
31 GRIN2A 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
32 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
33 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
34 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
35 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
36 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
37 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
38 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
39 GRIN2B 2件: Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
40 GRIN2C 1件: Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
41 GRIN2C 1件: Spinocerebellar ataxia D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
42 GRIN2C 1件: Spinocerebellar ataxia D07058 Acamprosate 2件: 6, 206
43 GRIN2C 1件: Spinocerebellar ataxia D07283 Esketamine 3件: 2, 4, 70
44 GRIN2C 1件: Spinocerebellar ataxia D07441 Amantadine 4件: 6, 8, 13, 127
45 GRIN2C 1件: Spinocerebellar ataxia D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
46 GRIN2C 1件: Spinocerebellar ataxia D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
47 GRIN2C 1件: Spinocerebellar ataxia D09917 Latrepirdine 1件: 8
48 GRIN2D 1件: Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
49 GRIN2D 1件: Spinocerebellar ataxia D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
50 GRIN2D 1件: Spinocerebellar ataxia D07058 Acamprosate 2件: 6, 206
51 GRIN2D 1件: Spinocerebellar ataxia D07283 Esketamine 3件: 2, 4, 70
52 GRIN2D 1件: Spinocerebellar ataxia D07441 Amantadine 4件: 6, 8, 13, 127
53 GRIN2D 1件: Spinocerebellar ataxia D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
54 GRIN2D 1件: Spinocerebellar ataxia D08174 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206
55 GRIN2D 1件: Spinocerebellar ataxia D09917 Latrepirdine 1件: 8
56 KCNC3 1件: Spinocerebellar ataxia D04127 Dalfampridine 5件: 3, 4, 6, 13, 14
57 KCNC3 1件: Spinocerebellar ataxia D10228 Amifampridine 3件: 3, 11, 12
58 KCND3 1件: Spinocerebellar ataxia D02910 Amiodarone 2件: 28, 127
59 KCND3 1件: Spinocerebellar ataxia D04127 Dalfampridine 5件: 3, 4, 6, 13, 14
60 KCND3 1件: Spinocerebellar ataxia D10228 Amifampridine 3件: 3, 11, 12
61 MAP3K5 4件: Tight junction, TNF signaling pathway, Thermogenesis, Spinocerebellar ataxia D10988 Selonsertib 1件: 86
62 PIK3CA 9件: VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11011 Alpelisib 1件: 138
63 PIK3CA 9件: VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
64 PIK3CB 9件: VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
65 PIK3CD 9件: VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib 2件: 53, 65
66 PIK3CD 9件: VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib 3件: 35, 53, 61
67 PRKCB 6件: Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Spinocerebellar ataxia D11935 Enzastaurin 1件: 168
68 PSMB5 1件: Spinocerebellar ataxia D03150 Bortezomib 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
69 PSMB5 1件: Spinocerebellar ataxia D08880 Carfilzomib 1件: 28
70 PSMB5 1件: Spinocerebellar ataxia D10130 Ixazomib 5件: 13, 16, 28, 51, 61