Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CDK4	9件: p53 signaling pathway, PI3K-Akt signaling pathway, Tight junction, T cell receptor signaling pat ...	D10688	Abemaciclib	1件: 34
2	CDK6	7件: p53 signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Viral carcinogenesis, Pan ...	D10688	Abemaciclib	1件: 34
3	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D01977	Gefitinib	1件: 75
4	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D03455	Cetuximab	2件: 51, 86
5	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D07907	Erlotinib	1件: 94
6	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D08108	Lapatinib	3件: 34, 74, 75
7	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D08950	Neratinib	1件: 34
8	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D11251	Icotinib	1件: 34
9	EGFR	15件: Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt sign ...	D11772	Tesevatinib	1件: 67
10	ERBB2	8件: Platinum drug resistance, PI3K-Akt signaling pathway, Tight junction, Pathways in cancer, Proteo ...	D08108	Lapatinib	3件: 34, 74, 75

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