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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CNR1
💬
1. CNR1
×
Name
Full Name
CNR1
cannabinoid receptor 1
[4]
Rap1 signaling pathway
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endocannabinoid signaling
[4]
Rap1 signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Retrograde endoc
...
Cannabidiol
Cannabidiol
💬
1. CNR1
×
Name
Other Names
Cannabidiol
Cannabidiol (USAN/INN)
Epidiolex (TN)
Cannabidiol
[20]
2
2
,
6
,
8
,
13
,
36
,
46
,
51
,
95
,
96
,
97
,
140
,
144
,
145
,
156
,
157
,
158
,
193
,
206
,
226
,
271
💬
1. CNR1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
51
Scleroderma
95
Autoimmune hepatitis
96
Crohn disease
97
Ulcerative colitis
140
Dorabe syndrome
144
Lennox-Gastaut syndrome
145
West syndrome
156
Rett syndrome
157
Sturge-Weber syndrome
158
Tuberous sclerosis
193
Prader-Willi syndrome
206
Fragile X syndrome
226
Interstitial cystitis with Hunners ulcer
271
Ankylosing spondylitis
2
CNR2
💬
2. CNR2
×
Name
Full Name
CNR2
cannabinoid receptor 2
[1]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
Cannabidiol
Cannabidiol
💬
2. CNR2
×
Name
Other Names
Cannabidiol
Cannabidiol (USAN/INN)
Epidiolex (TN)
Cannabidiol
[20]
2
2
,
6
,
8
,
13
,
36
,
46
,
51
,
95
,
96
,
97
,
140
,
144
,
145
,
156
,
157
,
158
,
193
,
206
,
226
,
271
💬
2. CNR2
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
51
Scleroderma
95
Autoimmune hepatitis
96
Crohn disease
97
Ulcerative colitis
140
Dorabe syndrome
144
Lennox-Gastaut syndrome
145
West syndrome
156
Rett syndrome
157
Sturge-Weber syndrome
158
Tuberous sclerosis
193
Prader-Willi syndrome
206
Fragile X syndrome
226
Interstitial cystitis with Hunners ulcer
271
Ankylosing spondylitis
3
ADRB1
💬
3. ADRB1
×
Name
Full Name
ADRB1
adrenoceptor beta 1
[11]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Gap junction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
[11]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive liga
...
Propranolol
Propranolol
💬
3. ADRB1
×
Name
Other Names
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol
[6]
6
6
,
158
,
167
,
227
,
278
,
296
💬
3. ADRB1
×
Disease ID
Name
6
Parkinson disease
158
Tuberous sclerosis
167
Marfan syndrome
227
Osler disease
278
Huge lymphatic malformation with cervicofacial lesion
296
Biliary atresia
4
ADRB2
💬
4. ADRB2
×
Name
Full Name
ADRB2
adrenoceptor beta 2
[9]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
[9]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
Propranolol
Propranolol
💬
4. ADRB2
×
Name
Other Names
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol
[6]
6
6
,
158
,
167
,
227
,
278
,
296
💬
4. ADRB2
×
Disease ID
Name
6
Parkinson disease
158
Tuberous sclerosis
167
Marfan syndrome
227
Osler disease
278
Huge lymphatic malformation with cervicofacial lesion
296
Biliary atresia
5
ADRB3
💬
5. ADRB3
×
Name
Full Name
ADRB3
adrenoceptor beta 3
[8]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Thermogenesis
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
[8]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Propranolol
Propranolol
💬
5. ADRB3
×
Name
Other Names
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol
[6]
6
6
,
158
,
167
,
227
,
278
,
296
💬
5. ADRB3
×
Disease ID
Name
6
Parkinson disease
158
Tuberous sclerosis
167
Marfan syndrome
227
Osler disease
278
Huge lymphatic malformation with cervicofacial lesion
296
Biliary atresia
6
ABAT
💬
6. ABAT
×
Name
Full Name
ABAT
4-aminobutyrate aminotransferase
[7]
Alanine, aspartate and glutamate metabolism
Alanine, aspartate and glutamate metabolism
,
Valine, leucine and isoleucine degradation
,
beta-Alanine metabolism
,
Propanoate metabolism
,
Butanoate metabolism
,
Metabolic pathways
,
GABAergic synapse
[7]
Alanine, aspartate and glutamate metabolism
,
Valine, leucine and isoleucine degradation
,
beta-Al
...
Vigabatrin
Vigabatrin
💬
6. ABAT
×
Name
Other Names
Vigabatrin
Vigabatrin (JAN/USP/INN)
Sabril (TN)
VIGABATRIN FOR ORAL SOLUTION
VIGABATRIN FOR ORAL SOLUTION USP, 500 MG
VIGADRONE
Vigabatrin
[2]
145
145
,
158
💬
6. ABAT
×
Disease ID
Name
145
West syndrome
158
Tuberous sclerosis
7
MTOR
💬
7. MTOR
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1 signaling pathway
,
Phospholipase D signaling pathway
,
Autophagy - other
,
Autophagy - animal
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Cellular senescence
,
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
JAK-STAT signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Insulin signaling pathway
,
Thyroid hormone signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Growth hormone synthesis, secretion and action
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Pathways of neurodegeneration - multiple diseases
,
Shigellosis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Colorectal cancer
,
Pancreatic cancer
,
Glioma
,
Prostate cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
[51]
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1
...
Sirolimus
Sirolimus
💬
7. MTOR
×
Name
Other Names
Sirolimus
Sirolimus (JAN/USAN/INN)
Rapamune (TN)
Rapamycin (TN)
FYARRO
HYFTOR
Sirolimus
[40]
2
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
,
98
,
137
,
157
,
158
,
192
,
193
,
222
,
256
,
277
,
278
,
279
,
280
,
281
,
283
,
300
,
331
💬
[40]
2
,
13
,
15
,
17
,
19
,
34
,
35
,
36
,
46
,
49
,
51
,
53
,
60
,
61
,
62
,
63
,
65
,
66
,
67
,
84
,
85
,
86
,
89
,
96
, ...
7. MTOR
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
13
Multiple sclerosis/Neuromyelitis optica
15
Inclusion body myositis
17
Multiple system atrophy
19
Lysosomal storage disease
34
Neurofibromatosis
35
Pemphigus
36
Epidermolysis bullosa
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
53
Sjogren syndrome
60
Aplastic anemia
61
Autoimmune hemolytic anemia
62
Paroxysmal nocturnal hemoglobinuria
63
Idiopathic thrombocytopenic purpura
65
Primary immunodeficiency
66
IgA nephropathy
67
Polycystic kidney disease
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
89
Lymphangioleiomyomatosis
96
Crohn disease
98
Eosinophilic gastrointestinal disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
192
Cockayne syndrome
193
Prader-Willi syndrome
222
Primary nephrotic syndrome
256
Muscle glycogenosis
277
Lymphangiomatosis
278
Huge lymphatic malformation with cervicofacial lesion
279
Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280
Huge arteriovenous malformation with cervicofacial or limb lesion
281
Klippel-Trenaunay-Weber syndrome
283
Acquired pure red cell aplasia
300
IgG4-related disease
331
Idiopathic multicentric castleman disease
8
MTOR
💬
8. MTOR
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1 signaling pathway
,
Phospholipase D signaling pathway
,
Autophagy - other
,
Autophagy - animal
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Cellular senescence
,
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
JAK-STAT signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Insulin signaling pathway
,
Thyroid hormone signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Growth hormone synthesis, secretion and action
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Pathways of neurodegeneration - multiple diseases
,
Shigellosis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Colorectal cancer
,
Pancreatic cancer
,
Glioma
,
Prostate cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
[51]
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1
...
Everolimus
Everolimus
💬
8. MTOR
×
Name
Other Names
Everolimus
Everolimus (JAN/USAN/INN)
Afinitor (TN)
Votubia (TN)
Zortress (TN)
Everolimus
[9]
34
34
,
67
,
89
,
96
,
137
,
157
,
158
,
228
,
277
💬
8. MTOR
×
Disease ID
Name
34
Neurofibromatosis
67
Polycystic kidney disease
89
Lymphangioleiomyomatosis
96
Crohn disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
228
Bronchiolitis obliterans
277
Lymphangiomatosis
9
GABRA1
💬
9. GABRA1
×
Name
Full Name
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
[6]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
[6]
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Ganaxolone
Ganaxolone
💬
9. GABRA1
×
Name
Other Names
Ganaxolone
Ganaxolone (USAN/INN)
Ztalmy (TN)
Ganaxolone
[4]
145
145
,
152
,
158
,
206
💬
9. GABRA1
×
Disease ID
Name
145
West syndrome
152
PCDH19 related syndrome
158
Tuberous sclerosis
206
Fragile X syndrome
10
GABRA2
💬
10. GABRA2
×
Name
Full Name
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
[6]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
,
Taste transduction
,
Morphine addiction
,
Nicotine addiction
[6]
Neuroactive ligand-receptor interaction
,
Retrograde endocannabinoid signaling
,
GABAergic synapse
...
Ganaxolone
Ganaxolone
💬
10. GABRA2
×
Name
Other Names
Ganaxolone
Ganaxolone (USAN/INN)
Ztalmy (TN)
Ganaxolone
[4]
145
145
,
152
,
158
,
206
💬
10. GABRA2
×
Disease ID
Name
145
West syndrome
152
PCDH19 related syndrome
158
Tuberous sclerosis
206
Fragile X syndrome