Target Gene/Pathway Pathway / Gene
Search results
Showing 1 to 10 of 27 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
IL17RA
💬1. IL17RA
| [3] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Alcoholic liver disease | Brodalumab
Brodalumab
💬1. IL17RA
| Brodalumab | [2] 37 37, 51 💬
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| 2 |
HPRT1
💬2. HPRT1
| [4] Purine metabolism Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism | Tioguanine
Tioguanine
💬2. HPRT1
| Tioguanine | [2] 13 13, 37 💬
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| 3 |
IL1R1
💬3. IL1R1
| [13] MAPK signaling pathway MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Shigellosis, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis [13] MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, O ... | Anakinra
Anakinra
💬3. IL1R1
| Anakinra | [18] 2 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬3. IL1R1
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| 4 |
IL12A
💬4. IL12A
| [25] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Alcoholic liver disease, Type I diabetes mellitus, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Measles, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Inflammatory bowel disease, Allograft rejection, Lipid and atherosclerosis [25] Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like recept ... | Ustekinumab
Ustekinumab
💬4. IL12A
| Ustekinumab | [16] 37 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬4. IL12A
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| 5 |
IL12B
💬5. IL12B
| [25] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Alcoholic liver disease, Type I diabetes mellitus, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, African trypanosomiasis, Toxoplasmosis, Amoebiasis, Tuberculosis, Measles, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, Inflammatory bowel disease, Allograft rejection, Lipid and atherosclerosis [25] Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like recept ... | Ustekinumab
Ustekinumab
💬5. IL12B
| Ustekinumab | [16] 37 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬5. IL12B
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| 6 |
IL17A
💬6. IL17A
| [6] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis [6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ... | Secukinumab
Secukinumab
💬6. IL17A
| Secukinumab | [8] 13 13, 37, 41, 46, 107, 160, 269, 271 💬
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| 7 |
IL17A
💬7. IL17A
| [6] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis [6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ... | Ixekizumab
Ixekizumab
💬7. IL17A
| Ixekizumab | [8] 36 36, 37, 46, 107, 160, 162, 269, 271 💬
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| 8 |
ITGAL
💬8. ITGAL
| [12] Rap1 signaling pathway Rap1 signaling pathway, Cell adhesion molecules, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Malaria, Staphylococcus aureus infection, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Rheumatoid arthritis, Viral myocarditis [12] Rap1 signaling pathway, Cell adhesion molecules, Neutrophil extracellular trap formation, Natur ... | Efalizumab
Efalizumab
💬8. ITGAL
| Efalizumab | [9] 11 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
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| 9 |
MTNR1A
💬9. MTNR1A
| [2] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Circadian entrainment | Melatonin
Melatonin
💬9. MTNR1A
| Melatonin | [12] 6 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬9. MTNR1A
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| 10 |
MTNR1B
💬10. MTNR1B
| [2] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Circadian entrainment | Melatonin
Melatonin
💬10. MTNR1B
| Melatonin | [12] 6 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬10. MTNR1B
|