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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
EDNRB
💬
1. EDNRB
×
Name
Full Name
EDNRB
endothelin receptor type B
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Melanogenesis
,
Relaxin signaling pathway
,
Pathways in cancer
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Bosentan
Bosentan
💬
1. EDNRB
×
Name
Other Names
Bosentan
Bosentan (USAN)
Bosentan hydrate (JAN)
Tracleer (TN)
Bosentan
[10]
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
1. EDNRB
×
Disease ID
Name
41
Giant cell arteritis
47
Buerger disease
51
Scleroderma
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
211
Hypoplastic left heart syndrome
212
Tricuspid atresia
2
EDNRB
💬
2. EDNRB
×
Name
Full Name
EDNRB
endothelin receptor type B
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Melanogenesis
,
Relaxin signaling pathway
,
Pathways in cancer
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Bosentan
Bosentan
💬
2. EDNRB
×
Name
Other Names
Bosentan
Bosentan (INN)
Bosentan
[10]
41
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
2. EDNRB
×
Disease ID
Name
41
Giant cell arteritis
47
Buerger disease
51
Scleroderma
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
211
Hypoplastic left heart syndrome
212
Tricuspid atresia
3
EDNRB
💬
3. EDNRB
×
Name
Full Name
EDNRB
endothelin receptor type B
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Melanogenesis
,
Relaxin signaling pathway
,
Pathways in cancer
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Macitentan
Macitentan
💬
3. EDNRB
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
Macitentan
[5]
51
51
,
85
,
86
,
88
,
210
💬
3. EDNRB
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
88
Chronic thromboembolic pulmonary hypertension
210
Single Ventricle
4
KIT
💬
4. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Dasatinib
Dasatinib
💬
4. KIT
×
Name
Other Names
Dasatinib
Dasatinib (JAN/INN)
Dasatinib
[2]
51
51
,
85
💬
4. KIT
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
5
KIT
💬
5. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Dasatinib
Dasatinib
💬
5. KIT
×
Name
Other Names
Dasatinib
Dasatinib (USAN)
Dasatinib hydrate (JAN)
Sprycel (TN)
Dasatinib
[2]
51
51
,
85
💬
5. KIT
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
6
KIT
💬
6. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Imatinib
Imatinib
💬
6. KIT
×
Name
Other Names
Imatinib
Imatinib (INN)
Glamox (TN)
Imatinib
[12]
13
13
,
28
,
34
,
35
,
46
,
51
,
85
,
86
,
87
,
88
,
89
,
162
💬
6. KIT
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
28
Systemic amyloidosis
34
Neurofibromatosis
35
Pemphigus
46
Malignant rheumatoid arthritis
51
Scleroderma
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
87
Pulmonary veno-occlusive disease
88
Chronic thromboembolic pulmonary hypertension
89
Lymphangioleiomyomatosis
162
Pemphigoid
7
KIT
💬
7. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Sorafenib
Sorafenib
💬
7. KIT
×
Name
Other Names
Sorafenib
Sorafenib (USAN/INN)
Sorafenib
[2]
34
34
,
86
💬
7. KIT
×
Disease ID
Name
34
Neurofibromatosis
86
Pulmonary arterial hypertension
8
KIT
💬
8. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Sunitinib
Sunitinib
💬
8. KIT
×
Name
Other Names
Sunitinib
Sunitinib (INN)
Sunitinib
[2]
28
28
,
34
💬
8. KIT
×
Disease ID
Name
28
Systemic amyloidosis
34
Neurofibromatosis
9
KIT
💬
9. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Nilotinib
Nilotinib
💬
9. KIT
×
Name
Other Names
Nilotinib
Nilotinib (USAN/INN)
Nilotinib
[5]
6
6
,
8
,
34
,
51
,
86
💬
9. KIT
×
Disease ID
Name
6
Parkinson disease
8
Huntington disease
34
Neurofibromatosis
51
Scleroderma
86
Pulmonary arterial hypertension
10
KIT
💬
10. KIT
×
Name
Full Name
KIT
KIT proto-oncogene, receptor tyrosine kinase
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signaling pathway
,
PI3K-Akt signaling pathway
,
Hematopoietic cell lineage
,
Melanogenesis
,
Pathways in cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Central carbon metabolism in cancer
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Phospholipase D signalin
...
Masitinib
Masitinib
💬
10. KIT
×
Name
Other Names
Masitinib
Masitinib (INN)
Masitinib
[6]
2
2
,
5
,
6
,
13
,
46
,
96
💬
10. KIT
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
5
Progressive supranuclear palsy
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
96
Crohn disease