Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MASP2	2件: Staphylococcus aureus infection, Coronavirus disease - COVID-19	D11531	Narsoplimab	4件: 64, 66, 109, 222
2	MAPK14	54件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D09639	Losmapimod	2件: 113, 222
3	MAPK14	54件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D10959	Neflamapimod	1件: 8
4	CSF2	14件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...	D11343	Otilimab	1件: 46
5	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D00251	Captopril	8件: 6, 17, 46, 86, 96, 97, 107, 271
6	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D00362	Lisinopril	7件: 19, 46, 49, 66, 67, 113, 222
7	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D00421	Ramipril	7件: 46, 49, 66, 67, 113, 218, 257
8	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D01069	Cilazapril	1件: 66
9	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D03752	Quinapril	1件: 19
10	ACE	5件: Renin-angiotensin system, Renin secretion, Coronavirus disease - COVID-19, Hypertrophic cardiomy ...	D03753	Perindopril	4件: 58, 113, 167, 222

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