Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...

Dronabinol 💬

[8] 2, 8, 13, 36, 46, 96, 271, 298 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
96	Crohn disease
271	Ankylosing spondylitis
298	Hereditary pancreatitis

2

[4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...

[3] 6, 13, 127 💬

3

[4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...

Rimonabant 💬

[1] 193 💬

4

[4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...

Cannabidiol 💬

[20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
51	Scleroderma
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
140	Dorabe syndrome
144	Lennox-Gastaut syndrome
145	West syndrome
156	Rett syndrome
157	Sturge-Weber syndrome
158	Tuberous sclerosis
193	Prader-Willi syndrome
206	Fragile X syndrome
226	Interstitial cystitis with Hunners ulcer
271	Ankylosing spondylitis

5

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

6

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

7

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Alprazolam 💬

[2] 8, 75 💬

8

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Clonazepam 💬

[1] 6 💬

9

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

[3] 46, 155, 298 💬

10

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

[1] 36 💬

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