Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

2

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

3

[29] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras si ...

Mecasermin 💬

[6] 65, 78, 96, 168, 265, 299 💬

4

[29] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras si ...

Teprotumumab 💬

[1] 51 💬

5

[29] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras si ...

Linsitinib 💬

[1] 232 💬

6

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...

Aminophylline 💬

[1] 63 💬

7

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...

Theophylline 💬

[2] 236, 299 💬

8

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...

[1] 294 💬

9

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...

[8] 2, 6, 21, 46, 78, 96, 97, 265 💬

10

[11] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...

[2] 2, 13 💬

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