Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 72 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
IL17F
💬1. IL17F
| [4] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Inflammatory bowel disease [4] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Infl ... | Bimekizumab
Bimekizumab
💬1. IL17F
| Bimekizumab | [3] 46 46, 97, 271 💬
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| 2 |
CNR1
💬2. CNR1
| [4] Rap1 signaling pathway Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ... | Dronabinol
Dronabinol
💬2. CNR1
| Dronabinol | [8] 2 2, 8, 13, 36, 46, 96, 271, 298 💬
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| 3 |
CNR1
💬3. CNR1
| [4] Rap1 signaling pathway Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ... | Cannabidiol
Cannabidiol
💬3. CNR1
| Cannabidiol | [20] 2 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬3. CNR1
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| 4 |
CNR2
💬4. CNR2
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Dronabinol
Dronabinol
💬4. CNR2
| Dronabinol | [8] 2 2, 8, 13, 36, 46, 96, 271, 298 💬
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| 5 |
CNR2
💬5. CNR2
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Cannabidiol
Cannabidiol
💬5. CNR2
| Cannabidiol | [20] 2 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬5. CNR2
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| 6 |
ACE
💬6. ACE
| [6] Renin-angiotensin system Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ... | Captopril
Captopril
💬6. ACE
| Captopril | [8] 6 6, 17, 46, 86, 96, 97, 107, 271 💬
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| 7 |
DHFR
💬7. DHFR
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬7. DHFR
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 7. DHFR
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| 8 |
DHODH
💬8. DHODH
| [3] Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Leflunomide
Leflunomide
💬8. DHODH
| Leflunomide | [12] 11 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬8. DHODH
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| 9 |
DHFR2
💬9. DHFR2
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬9. DHFR2
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 9. DHFR2
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| 10 |
FDPS
💬10. FDPS
| [4] Terpenoid backbone biosynthesis Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 ... | Alendronic acid
Alendronic acid
💬10. FDPS
| Alendronic acid | [7] 19 19, 41, 46, 50, 271, 274, 299 💬
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