Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

2

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

3

[32] Proteasome, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, TGF-b ...

Fontolizumab 💬

[1] 46 💬

4

[32] Proteasome, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, TGF-b ...

Emapalumab 💬

[3] 49, 65, 107 💬

5

[18] Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differ ...

Interferon gamma-1b 💬

Interferon gamma-1b

[7] 18, 65, 85, 228, 299, 301, 326 💬

6

[17] Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differ ...

Interferon gamma-1b 💬

Interferon gamma-1b

[7] 18, 65, 85, 228, 299, 301, 326 💬

7

[11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...

Aldesleukin 💬

[6] 2, 35, 49, 65, 96, 97 💬

8

[11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...

Basiliximab 💬

[6] 2, 50, 66, 97, 222, 228 💬

9

[11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...

Daclizumab 💬

[8] 13, 56, 60, 65, 97, 107, 283, 284 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
56	Behcet disease
60	Aplastic anemia
65	Primary immunodeficiency
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia

10

[11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine re ...

Aldesleukin 💬

[6] 2, 35, 49, 65, 96, 97 💬

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