DDrare
Disease
Drug
Target Gene/Pathway
Contact
JA
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 111 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
[28]
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[28]
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
1. CDK4
×
Disease ID
Name
34
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
[23]
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[23]
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
2. CDK6
×
Disease ID
Name
34
Neurofibromatosis
3
CRHR1
💬
3. CRHR1
×
Name
Full Name
CRHR1
corticotropin releasing hormone receptor 1
[4]
cAMP signaling pathway
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Long-term depression
,
Cushing syndrome
[4]
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Long-term depression
,
Cushing s
...
Corticorelin ovine triflutate
Corticorelin ovine triflutate
💬
3. CRHR1
×
Name
Other Names
Corticorelin ovine triflutate
Corticorelin ovine triflutate (USAN)
Acthrel (TN)
Corticorelin ovine triflutate
[1]
75
75
💬
3. CRHR1
×
Disease ID
Name
75
Cushing disease
4
CRHR1
💬
4. CRHR1
×
Name
Full Name
CRHR1
corticotropin releasing hormone receptor 1
[4]
cAMP signaling pathway
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Long-term depression
,
Cushing syndrome
[4]
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Long-term depression
,
Cushing s
...
Corticorelin
Corticorelin
💬
4. CRHR1
×
Name
Other Names
Corticorelin
Corticorelin (human) (JAN)
Xerecept
hCRH (TN)
Corticorelin
[1]
75
75
💬
4. CRHR1
×
Disease ID
Name
75
Cushing disease
5
CRHR2
💬
5. CRHR2
×
Name
Full Name
CRHR2
corticotropin releasing hormone receptor 2
[3]
cAMP signaling pathway
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Cushing syndrome
Corticorelin ovine triflutate
Corticorelin ovine triflutate
💬
5. CRHR2
×
Name
Other Names
Corticorelin ovine triflutate
Corticorelin ovine triflutate (USAN)
Acthrel (TN)
Corticorelin ovine triflutate
[1]
75
75
💬
5. CRHR2
×
Disease ID
Name
75
Cushing disease
6
CRHR2
💬
6. CRHR2
×
Name
Full Name
CRHR2
corticotropin releasing hormone receptor 2
[3]
cAMP signaling pathway
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Cushing syndrome
Corticorelin
Corticorelin
💬
6. CRHR2
×
Name
Other Names
Corticorelin
Corticorelin (human) (JAN)
Xerecept
hCRH (TN)
Corticorelin
[1]
75
75
💬
6. CRHR2
×
Disease ID
Name
75
Cushing disease
7
CYP11A1
💬
7. CYP11A1
×
Name
Full Name
CYP11A1
cytochrome P450 family 11 subfamily A member 1
[6]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
[6]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis
...
Levoketoconazole
Levoketoconazole
💬
7. CYP11A1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
Levoketoconazole
[1]
75
75
💬
7. CYP11A1
×
Disease ID
Name
75
Cushing disease
8
CYP11B1
💬
8. CYP11B1
×
Name
Full Name
CYP11B1
cytochrome P450 family 11 subfamily B member 1
[4]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing syndrome
[4]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing synd
...
Metyrapone
Metyrapone
💬
8. CYP11B1
×
Name
Other Names
Metyrapone
Metyrapone (JP18/USP/INN)
Metopirone (TN)
Metyrapone
[1]
75
75
💬
8. CYP11B1
×
Disease ID
Name
75
Cushing disease
9
CYP11B1
💬
9. CYP11B1
×
Name
Full Name
CYP11B1
cytochrome P450 family 11 subfamily B member 1
[4]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing syndrome
[4]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Cortisol synthesis and secretion
,
Cushing synd
...
Levoketoconazole
Levoketoconazole
💬
9. CYP11B1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
Levoketoconazole
[1]
75
75
💬
9. CYP11B1
×
Disease ID
Name
75
Cushing disease
10
CYP17A1
💬
10. CYP17A1
×
Name
Full Name
CYP17A1
cytochrome P450 family 17 subfamily A member 1
[6]
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling pathway
,
Cortisol synthesis and secretion
,
Cushing syndrome
[6]
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling p
...
Ketoconazole
Ketoconazole
💬
10. CYP17A1
×
Name
Other Names
Ketoconazole
Ketoconazole (JP18/USP)
Nizoral (TN)
Xolegel (TN)
Ketoconazole
[3]
8
8
,
13
,
75
💬
10. CYP17A1
×
Disease ID
Name
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
75
Cushing disease