Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir
(Synonym: Apo-abacavir-lamivudine-zidovudine)		4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen1件: D07057 --5件: 2, 135, 256, 265, 325
2 Abiraterone
(Synonym: Apo-abiraterone Acetate Film Coated Tablets)		3件: Abiraterone; Abiraterone acetate; ZYTIGA---2件: 75, 81
3 Acetaminophen
(Synonym: Isometheptene-Dichloral-APAP Oral)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
4 Acetylsalicylic acid
(Synonym: Apo Asa Tab 325mg)		2件: Acetylsalicylic Acid; Aspirin1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
5 Acyclovir
(Synonym: Apo-acyclovir)		3件: Aciclovir; Acycloguanosine; Acyclovir1件: D00222 --5件: 13, 28, 46, 53, 60
6 Adenosine
(Synonym: Applicell Miracle)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
7 Alendronic acid
(Synonym: Apo-alendronate)		3件: Alendronate; Alendronate sodium; Alendronic acid1件: D07119 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299
8 Alfuzosin
(Synonym: Apo-alfuzosin)		1件: Alfuzosin1件: D07124 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13
9 Allopurinol
(Synonym: Apo-allopurinol)		2件: Allopurinol; ALLOPURINOL SODIUM1件: D00224 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬7件: 6, 46, 57, 60, 66, 96, 97
10 Alprazolam
(Synonym: Apo-alpraz)		1件: Alprazolam1件: D00225 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75
11 Ambrisentan
(Synonym: Apo-ambrisentan)		3件: AMBRISENTAN; Letairis; VOLIBRIS1件: D07077 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 51, 84, 85, 86, 88, 210, 211
12 Aminopterin
(Synonym: APGA)		1件: Aminopterin---1件: 46
13 Amiodarone
(Synonym: Apo-amiodarone Tablets)		1件: AMIODARONE1件: D02910 16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127
14 Amitriptyline
(Synonym: Apo-amitriptyline)		3件: Amitriptylin; AMITRIPTYLINE; Amitriptyline hydrochloride1件: D07448 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
15 Amlodipine
(Synonym: Apo-amlodipine)		1件: Amlodipine1件: D07450 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
16 Amoxicillin
(Synonym: Apo-amoxicillin)		4件: Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin2件: D00229 ,
D07452 		--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
17 Ampicillin
(Synonym: Apo Ampi Liq 125mg/5ml)		1件: ABPC1件: D00204 --5件: 2, 6, 13, 84, 299
18 Anastrozole
(Synonym: Apo-anastrozole)		2件: Anastrozole; Arimidex1件: D00960 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
19 Apabetalone 1件: Apabetalone1件: D11131 (Name: Apabetalone)4件: BRD2,
BRD3,
BRD4,
BRDT 💬		-1件: 86
20 Apadamtase alfa 1件: Apadamtase alfa---1件: 64
21 Apigenin 1件: Apigenin---2件: 6, 97
22 Apitegromab 1件: Apitegromab1件: D11797 (Name: Apitegromab)1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
23 Apixaban 2件: Apixaban; Eliquis1件: D03213 (Name: Apixaban)1件: F10 💬1件: Complement and coagulation cascades 💬1件: 222
24 Aplindore 1件: Aplindore---1件: 6
25 Apomorphine 4件: APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride1件: D07460 (Name: Apomorphine)2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
26 Apraclonidine 1件: Apraclonidine1件: D07461 (Name: Apraclonidine)3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 11
27 Apratastat 1件: Apratastat1件: D08859 (Name: Apratastat)2件: ADAM17,
MMP13 💬		7件: Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬1件: 46
28 Apremilast 2件: Apremilast; Otezla1件: D08860 (Name: Apremilast)4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
29 Aprotinin 1件: Aprotinin1件: D02971 (Name: Aprotinin)--1件: 28
30 Aripiprazole
(Synonym: Apo-aripiprazole)		1件: Aripiprazole1件: D01164 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
31 Ascorbic acid
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		4件: Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
32 Atazanavir
(Synonym: Apo-atazanavir)		2件: Atazanavir; Reyataz1件: D07471 --1件: 265
33 Atenolol
(Synonym: Apo-atenol Tab 50mg)		1件: ATENOLOL1件: D00235 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
34 Atomoxetine
(Synonym: Apo-atomoxetine)		2件: Atomoxetine; Strattera1件: D07473 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
35 Atorvastatin
(Synonym: Apo-atorvastatin)		3件: Atorvastatin; Atorvastatin calcium; Lipitor1件: D07474 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
36 Atovaquone
(Synonym: Apo-atovaquone)		1件: ATOVAQUONE1件: D00236 --1件: 61
37 Azathioprine
(Synonym: Apo-azathioprine)		3件: Azathioprine; Azatioprina; Imuran1件: D00238 --21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
38 Azithromycin
(Synonym: Apo-azithromycin Z)		5件: AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX2件: D06390 ,
D07486 		--6件: 13, 84, 85, 96, 228, 299
39 Baclofen
(Synonym: Apo-baclofen)		2件: Baclofen; Kemstro1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬8件: 2, 10, 13, 18, 65, 70, 149, 206
40 Beclomethasone dipropionate
(Synonym: Apo-beclomethasone Nasal Spray)		2件: BECLOMETASONE DIPROPIONATE; Beclomethasone dipropionate1件: D00689 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 85, 97, 98
41 Bisacodyl
(Synonym: Apo-bisacodyl)		1件: Bisacodyl1件: D00245 --1件: 13
42 Bisoprolol
(Synonym: Apo-bisoprolol)		2件: Bisoprolol; Bisoprolol Fumarate1件: D02342 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 58, 67, 86, 113
43 Bosentan
(Synonym: Apo-bosentan)		2件: Bosentan; TRACLEER2件: D01227 ,
D07538 		2件: EDNRA,
EDNRB 💬		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
44 Brimonidine
(Synonym: Apo-brimonidine-timop)		2件: Brimonidine; Brimonidine Tartrate1件: D07540 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
45 Bupropion
(Synonym: Aplenzin ER)		2件: Bupropion; Bupropion Hydrochloride1件: D07591 2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 8, 18, 21, 96, 171
46 Buspirone
(Synonym: Apo-buspirone)		2件: Buspirone; Buspirone Hydrochloride1件: D07593 2件: DRD2,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 51
47 Cabergoline
(Synonym: Apo-cabergoline)		3件: CABERGOLINA; CABERGOLINE; DOSTINEX1件: D00987 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
48 Cabotegravir
(Synonym: Apretude)		1件: Cabotegravir1件: D10548 (Name: APRETUDE)--1件: 256
49 Caffeine
(Synonym: Apo-acetaco #1)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
50 Calcium carbonate
(Synonym: Apcal)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
51 Candesartan cilexetil
(Synonym: Apo-candesartan)		1件: CANDESARTAN1件: D00626 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 67
52 Capsaicin
(Synonym: Capsaicin No-Fuss Applicator)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
53 Captopril
(Synonym: Apo-capto Tab 25mg)		1件: Captopril1件: D00251 (Name: Apopril (TN))1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
54 Carbamazepine
(Synonym: Apo-carbamazepine CR)		1件: Carbamazepine1件: D00252 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
55 Carbidopa
(Synonym: Apo-levocarb - Tab 25mg/250mg)		8件: CARBIDOPA; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
56 Carvedilol
(Synonym: Apo-carvedilol)		1件: Carvedilol1件: D00255 5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 86, 113, 210
57 Cefadroxil
(Synonym: Apo-cefadroxil)		0件: 2件: D00257 ,
D02353 		--2件: 222, 240
58 Cefepime
(Synonym: Apo-cefepime)		1件: Cefepime1件: D02376 --2件: 60, 299
59 Cefuroxime
(Synonym: Apo-cefuroxime)		2件: Cefuroxim; CEFUROXIME1件: D00262 --2件: 97, 299
60 Celecoxib
(Synonym: Apo-celecoxib)		2件: Celebrex; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
61 Cephalexin
(Synonym: Apo-cephalex)		2件: CEFALEXIN; Cephalexin2件: D00263 ,
D00906 		--1件: 299
62 Cetirizine
(Synonym: Apo-cetirizine)		3件: CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: D07662 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
63 Chlorhexidine
(Synonym: Soluprep Applicator)		2件: Chlorhexidine; Chlorhexidine Gluconate1件: D07668 --2件: 86, 299
64 Chlorpheniramine
(Synonym: Aphedrid Cold and Allergy)		1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
65 Chlorpromazine
(Synonym: Apo Chlorpromazine)		2件: Chlorpromazine; Chlorpromazine Hydrochloride1件: D00270 13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
66 Cholecalciferol
(Synonym: Apo-alendronate/vitamin D3)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
67 Ciclesonide
(Synonym: Apo-ciclesonide)		1件: Ciclesonide1件: D01703 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
68 Cilazapril
(Synonym: Apo-cilazapril/hctz)		1件: Cilazapril2件: D01069 ,
D07699 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 66
69 Cimetidine
(Synonym: Apo-cimetidine Oral Solution)		1件: Cimetidine1件: D00295 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
70 Cinacalcet
(Synonym: Apo-cinacalcet)		1件: Cinacalcet1件: D03504 1件: CASR 💬2件: NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬1件: 238
71 Ciprofloxacin
(Synonym: Apo-ciproflox)		2件: CIPROFLOXACIN; Ciprofloxacin hydrochloride1件: D00186 --5件: 2, 60, 96, 97, 299
72 Citalopram
(Synonym: Apo-citalopram)		1件: Citalopram1件: D07704 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
73 Clarithromycin
(Synonym: Apo-clarithromycin XL)		1件: CLARITHROMYCIN1件: D00276 --8件: 6, 63, 84, 96, 97, 222, 228, 299
74 Clavulanic acid
(Synonym: Apo-amoxicillin-clavulanate)		4件: AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID1件: D07711 --1件: 299
75 Clindamycin
(Synonym: Apo-clindamycin)		2件: CLINDAMYCIN; Dalacin C phosphate1件: D00277 --2件: 46, 299
76 Clobazam
(Synonym: Apo-clobazam)		1件: Clobazam1件: D01253 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 140, 144
77 Clobetasol propionate
(Synonym: Dermovate Scalp Application)		1件: Clobetasol Propionate1件: D01272 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 162
78 Clonazepam
(Synonym: Apo-clonazepam)		1件: Clonazepam1件: D00280 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
79 Clonidine
(Synonym: Apo-clonidine)		4件: Clonidin; Clonidina; Clonidine; Clonidine hydrochloride1件: D00281 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
80 Clopidogrel
(Synonym: Apo-clopidogrel)		1件: Clopidogrel3件: D07729 ,
D10823 ,
D10824 		1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86
81 Colesevelam
(Synonym: Apo-colesevelam)		2件: Cholestagel; Colesevelam1件: D07743 --2件: 96, 260
82 Cromoglicic acid
(Synonym: Apo-cromolyn Nasal Spray)		4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium1件: D07753 --3件: 2, 85, 98
83 Cyclosporine
(Synonym: Apo-cyclosporine Oral Solution)		10件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
84 D-glucose
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
85 Dabigatran etexilate
(Synonym: Apo-dabigatran)		1件: Dabigatran etexilate1件: D07144 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬2件: 51, 75
86 Dalfampridine
(Synonym: 4-AP)		7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
87 Darifenacin
(Synonym: Apo-darifenacin)		2件: Darifenacin; Emselex1件: D03654 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
88 Darunavir
(Synonym: Apo-darunavir)		1件: Darunavir1件: D03656 --1件: 2
89 Dasatinib
(Synonym: Apo-dasatinib)		1件: Dasatinib2件: D03658 ,
D06414 		8件: ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		77件: Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 51, 85
90 Deferasirox
(Synonym: Apo-deferasirox)		2件: DEFERASIROX; EXJADE1件: D03669 --3件: 254, 284, 286
91 Desmopressin
(Synonym: Apo-desmopressin)		5件: DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
92 Desogestrel
(Synonym: Apri 28)		2件: Desogestrel; Désogestrel1件: D02367 2件: ESR1,
PGR 💬		11件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 230
93 Dexamethasone
(Synonym: Apo-dexamethasone)		5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
94 Dextromethorphan
(Synonym: AP-Hist DM)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
95 Diclofenac
(Synonym: Apo-diclofenac Ophthalmic)		3件: Diclofenac; Diclofenac Sodium; Diclofenac SR1件: D07816 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
96 Digoxin
(Synonym: Apo-digoxin)		1件: Digoxin1件: D00298 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210
97 Diltiazem
(Synonym: Apo-diltiaz Injectable)		2件: Diltiazem; Diltiazem Hydrochloride1件: D07845 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
98 Dimethyl fumarate
(Synonym: Apo-dimethyl Fumarate)		3件: Dimethyl fumarate; Dimethylfumarat; TECFIDERA1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296
99 Diphenhydramine
(Synonym: Aphenap)		2件: Diphenhydramine; Diphenhydramine hydrochloride1件: D00300 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256
100 Dipivefrin
(Synonym: Apo-dipivefrin)		2件: Dipivefrin; Dipivefrine1件: D02349 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
101 Dipyridamole
(Synonym: Apo-dipyridamole)		1件: Dipyridamole1件: D00302 2件: PDE4A,
PDE5A 💬		6件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 46, 49, 51, 66, 96, 224
102 Domperidone
(Synonym: Apo-domperidone - Tab 10mg)		1件: Domperidone2件: D01745 ,
D07868 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
103 Donepezil
(Synonym: Apo-donepezil)		3件: Aricept; Donepezil; Donepezil Hydrochloride1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
104 Dorzolamide
(Synonym: Apo-dorzolamide)		1件: Dorzolamide1件: D07871 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
105 Doxazosin
(Synonym: Apo-doxazosin)		2件: CARDURA; Doxazosin1件: D07874 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 67
106 Doxycycline
(Synonym: Apprilon)		4件: Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets2件: D00307 ,
D07876 		--17件: 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
107 Duloxetine
(Synonym: Apo-duloxetine)		3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride1件: D07880 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
108 Dutasteride
(Synonym: Apo-dutasteride)		2件: Dutasterida; Dutasteride1件: D03820 2件: SRD5A1,
SRD5A2 💬		3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬2件: 1, 2
109 Efavirenz
(Synonym: Apo-efavirenz-emtricitabine-tenofovir)		2件: Efavirenz; SUSTIVA1件: D00896 --1件: 265
110 Emtricitabine
(Synonym: Apo-emtricitabine-tenofovir)		2件: Emtricitabine; TRUVADA1件: D01199 --4件: 25, 93, 265, 325
111 Enalapril
(Synonym: Apo-enalapril Tab 5mg)		2件: Enalapril; Enalapril Maleate1件: D07892 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222
112 Entacapone
(Synonym: Apo-entacapone)		5件: COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo1件: D00781 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17
113 Entecavir
(Synonym: Apo-entecavir)		1件: Entecavir2件: D04008 ,
D07896 		--6件: 46, 56, 96, 97, 107, 271
114 Eplerenone
(Synonym: Apo-eplerenone)		1件: Eplerenone1件: D01115 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215
115 Erlotinib
(Synonym: Apo-erlotinib)		1件: Erlotinib1件: D07907 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 94
116 Escitalopram
(Synonym: Apo-escitalopram)		3件: Citalopram; Escitalopram; Escitalopram oxalate1件: D07913 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46
117 Esomeprazole
(Synonym: Apo-esomeprazole)		3件: Esomeprazole; Nexium; Omeprazole1件: D07917 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
118 Ethanol
(Synonym: Anti-Bacterial Hand Gel Candy Apple)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
119 Ethinylestradiol
(Synonym: Apri 28)		3件: Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 7771件: D00554 1件: ESR1 💬9件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 13, 46, 49, 299
120 Etidronic acid
(Synonym: Apo-etidronate)		1件: Etidronate1件: D02373 --1件: 27
121 Ezetimibe
(Synonym: Apo-ezetimibe)		2件: Ezetimibe; Ezetrol1件: D01966 1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260
122 Factor IX Complex (Human)
(Synonym: APCC)		1件: Prothrombin Complex Concentrate---1件: 288
123 Famciclovir
(Synonym: Apo-famciclovir)		1件: Famciclovir1件: D00317 --2件: 11, 13
124 Famotidine
(Synonym: Apo-famotidine)		2件: FAMOTIDINA; Famotidine1件: D00318 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107
125 Fentanyl
(Synonym: Apo-fentanyl Matrix)		1件: Fentanyl1件: D00320 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬3件: 46, 70, 215
126 Fesoterodine
(Synonym: Apo-fesoterodine)		1件: Fesoterodine1件: D07226 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
127 Finasteride
(Synonym: Apo-finasteride)		1件: Finasteride1件: D00321 1件: SRD5A2 💬3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬1件: 6
128 Fingolimod
(Synonym: Apo-fingolimod)		3件: Fingolimod; FINGOLIMOD HYDROCHLORIDE; Gilenya1件: D10001 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 14, 156
129 Flavoxate
(Synonym: Apo-flavoxate)		1件: Flavoxate1件: D07961 16件: PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		18件: Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 226
130 Flecainide
(Synonym: Apo-flecainide)		3件: Flecainide; FLECAINIDE ACETATE; Flecainidum1件: D07962 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
131 Fluconazole
(Synonym: Apo-fluconazole)		2件: Diflucan; FLUCONAZOLE1件: D00322 --2件: 96, 225
132 Fluoxetine
(Synonym: Apo-fluoxetine)		5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC1件: D00326 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
133 Fluticasone propionate
(Synonym: Apo-fluticasone)		3件: Flovent; Fluticasone; Fluticasone propionate1件: D01708 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228
134 Fulvestrant
(Synonym: Apo-fulvestrant)		2件: Faslodex; Fulvestrant1件: D01161 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 49, 86
135 Furosemide
(Synonym: Apo-furosemide)		2件: Furosemide; Furosemide Injection1件: D00331 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 6, 86
136 Gabapentin
(Synonym: Apo-gabapentin)		4件: GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
137 Galantamine
(Synonym: Apo-galantamine)		2件: GALANTAMINE; Galantamine hydrobromide1件: D04292 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
138 Gefitinib
(Synonym: Apo-gefitinib)		1件: Gefitinib1件: D01977 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 75
139 Glycerin
(Synonym: Derm-apply)		2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
140 Guanfacine
(Synonym: Apo-guanfacine XR)		1件: Guanfacine1件: D08031 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
141 Haloperidol
(Synonym: Apo-haloperidol LA Injectable)		1件: Haloperidol1件: D00136 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 8
142 Hydralazine
(Synonym: Apo-hydralazine)		1件: Hydralazine1件: D08044 1件: AOC3 💬5件: Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬1件: 67
143 Hydrochlorothiazide
(Synonym: Apo Methazide 25)		2件: Esidrix; HYDROCHLOROTHIAZIDE1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
144 Hydrocortisone
(Synonym: Apres Peel Soothing Balm)		6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
145 Hydromorphone
(Synonym: Apo-hydromorphone)		1件: Hydromorphone1件: D08047 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
146 Hydroxychloroquine
(Synonym: Apo-hydroxyquine)		3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; PLAQUENIL1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
147 Hydroxyurea
(Synonym: Apo-hydroxyurea)		1件: Hydroxyurea1件: D00341 1件: RRM2 💬7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284
148 Ibuprofen
(Synonym: Apo-ibuprofen Tab 600mg)		2件: Ibuprofen; IBUPROFEN 200MG1件: D00126 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
149 Imatinib
(Synonym: Apo-imatinib)		4件: Gleevec; GLIVEC; Imatinib; IMATINIB MESYLATE1件: D08066 3件: ABL1,
KIT,
PDGFRA 💬		32件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
150 Imiquimod
(Synonym: Apo-imiquimod)		1件: Imiquimod1件: D02500 1件: TLR7 💬5件: Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬2件: 34, 51
151 Indapamide
(Synonym: Apo-perindopril-indapamide)		1件: Indapamide1件: D00345 1件: SLC12A3 💬-1件: 13
152 Indomethacin
(Synonym: Apo Indomethacin Cap 25mg)		2件: INDOMETACIN; Indomethacin1件: D00141 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298
153 Ipratropium
(Synonym: Apo-ipravent Solution - Inh 250mcg/ml)		1件: Ipratropium---2件: 6, 86
154 Irbesartan
(Synonym: Apo-irbesartan/hctz)		2件: Aprovel; IRBESARTAN1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222
155 Ketoconazole
(Synonym: Apo-ketoconazole)		2件: KETOCONAZOLE; NIZORAL1件: D00351 1件: CYP17A1 💬6件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬3件: 8, 13, 75
156 Ketorolac
(Synonym: Apo-ketorolac Injectable)		2件: Ketorolac; Ketorolac Tromethamine1件: D08104 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 70, 226
157 Lacosamide
(Synonym: Apo-lacosamide)		1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬4件: 2, 46, 149, 298
158 Lamivudine
(Synonym: Apo-abacavir-lamivudine Tablets)		4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --8件: 2, 26, 42, 46, 135, 256, 265, 325
159 Lamotrigine
(Synonym: Apo-lamotrigine)		2件: Lamictal; LAMOTRIGINE1件: D00354 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 13, 34, 38, 114, 144
160 Lansoprazole
(Synonym: Apo-lansoprazole)		1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
161 Leflunomide
(Synonym: Apo-leflunomide)		3件: ARAVA; Leflunomide; Leflunomidum1件: D00749 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
162 Lenalidomide
(Synonym: Apo-lenalidomide)		2件: Lenalidomide; REVLIMID1件: D04687 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 16, 26, 28, 34, 49, 284, 300, 331
163 Letrozole
(Synonym: Apo-letrozole)		1件: Letrozole1件: D00964 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89
164 Levetiracetam
(Synonym: Apo-levetiracetam)		2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
165 Levodopa
(Synonym: Apo-levocarb-tab 25mg/100mg)		9件: Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬6件: 6, 17, 90, 140, 164, 201
166 Levofloxacin
(Synonym: Apo-levofloxacin)		2件: Levaquin; Levofloxacin2件: D00588 ,
D08120 		--5件: 46, 53, 84, 85, 299
167 Lidocaine
(Synonym: Aspercreme with Lidocaine No-Mess Applicator)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
168 Linezolid
(Synonym: Apo-linezolid)		1件: LINEZOLID1件: D00947 --1件: 299
169 Lisinopril
(Synonym: Apo-lisinopril Tablet - 5mg)		2件: Lisinopril; Zestril2件: D00362 ,
D08131 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222
170 Lithium carbonate
(Synonym: Apo-lithium Carbonate)		2件: Lithium; LITHIUM CARBONATE1件: D00801 --5件: 2, 13, 17, 18, 127
171 Loperamide
(Synonym: Apo-loperamide)		2件: LOPERAMIDE; Loperamide hydrochloride1件: D08144 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97
172 Loratadine
(Synonym: Apo-loratadine)		2件: Loratadina; LORATADINE1件: D00364 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98
173 Lorazepam
(Synonym: Apo-lorazepam Tab 1mg)		1件: Lorazepam1件: D00365 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 36
174 Losartan
(Synonym: Apo-losartan)		3件: Cozaar; Losartan; Losartan Potassium1件: D08146 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
175 Magnesium oxide
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		1件: Magnesium oxide1件: D01167 --3件: 6, 166, 291
176 Medroxyprogesterone acetate
(Synonym: Apo-medroxy Tablets)		1件: Medroxyprogesterone1件: D00951 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬8件: 13, 35, 46, 49, 50, 51, 60, 107
177 Megestrol acetate
(Synonym: Apo-megestrol)		1件: Megestrol acetate1件: D00952 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 76
178 Meloxicam
(Synonym: Apo-meloxicam)		1件: Meloxicam1件: D00969 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296
179 Memantine
(Synonym: Apo-memantine)		3件: Ebixa; MEMANTINE; MEMANTINE HYDROCHLORIDE1件: D08174 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206
180 Mesalazine
(Synonym: Apriso)		10件: 5-AminoSalicylic Acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk1件: D00377 (Name: Apriso (TN))--5件: 46, 96, 97, 98, 164
181 Metformin
(Synonym: Apo-metformin ER)		5件: Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
182 Methimazole
(Synonym: Apo-methimazole)		1件: Methimazole1件: D00401 1件: TPO 💬4件: Autoimmune thyroid disease, Metabolic pathways, Thyroid hormone synthesis, Tyrosine metabolism 💬1件: 50
183 Methotrexate
(Synonym: Apo-methotrexate)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate1件: D00142 2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
184 Methylphenidate
(Synonym: Apo-methylphenidate SR)		3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin1件: D04999 2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206
185 Metoclopramide
(Synonym: Apo-metoclop Tab 10mg)		1件: METOCLOPRAMIDE1件: D00726 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 46, 51
186 Metoprolol
(Synonym: Apo-metoprolol)		2件: Metoprolol; METOPROLOL SUCCINATE1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
187 Metronidazole
(Synonym: Apo-metronidazole)		3件: Flagyl; Metronidazol; Metronidazole1件: D00409 --7件: 46, 51, 63, 94, 96, 97, 291
188 Midazolam
(Synonym: Apo-midazolam Injectable 1 mg/ml)		2件: Midazolam; Midazolam injection1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
189 Midodrine
(Synonym: Apo-midodrine)		2件: Midodrine; MIDODRINE HYDROCHLORIDE1件: D08220 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
190 Milrinone
(Synonym: Apo-milrinone Injectable)		1件: Milrinone1件: D00417 2件: PDE3A,
PDE3B 💬		11件: Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 294
191 Mineral oil
(Synonym: Apj Hemorrhoidal)		1件: Paraffin Oil1件: D05042 --1件: 291
192 Minoxidil
(Synonym: Apo-gain Liq 20mg/ml)		1件: MINOXIDIL1件: D00418 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179
193 Modafinil
(Synonym: Apo-modafinil)		2件: Modafinil; Provigil1件: D01832 --5件: 6, 13, 49, 93, 113
194 Mometasone furoate
(Synonym: Apo-mometasone)		3件: Mometasone; MOMETASONE FUROATE; Nasonex1件: D00690 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
195 Montelukast
(Synonym: Apo-montelukast Sodium Chewable)		3件: Montelukast; MONTELUKAST SODIUM; Singulair1件: D08229 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
196 Moxifloxacin
(Synonym: Apo-moxifloxacin)		2件: Moxifloxacin; Moxifloxacin Hydrochloride1件: D08237 --9件: 2, 6, 46, 49, 85, 86, 113, 240, 299
197 Mycophenolate mofetil
(Synonym: Apo-mycophenolate Mofetil)		3件: CellCept; Mycophenolate Mofetil; Mycophenolate mofetil TEVA1件: D00752 2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
198 Mycophenolic acid
(Synonym: Apo-mycophenolic Acid)		5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic1件: D05096 2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
199 Nabilone
(Synonym: Apo-nabilone)		1件: NABILONE1件: D05099 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127
200 Nadolol
(Synonym: Apo-nadolol)		1件: Nadolol1件: D00432 2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
201 Naltrexone
(Synonym: Apo-naltrexone)		2件: Naltrexone; Naltrexone Hydrochloride1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
202 Naproxen
(Synonym: Apo Naproxen Tab 125mg)		5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
203 Nebivolol
(Synonym: Apo-nebivolol)		1件: Nebivolol1件: D05127 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167
204 Neomycin
(Synonym: Antibiotic Application)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
205 Nevirapine
(Synonym: Apo-zidovudine-lamivudine-nevirapine)		1件: Nevirapine1件: D00435 --1件: 265
206 Nicotinamide
(Synonym: Appedrine)		3件: Multivitamin; Niacinamide; Nicotinamide1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
207 Nifedipine
(Synonym: Apo-nifed Pa)		1件: Nifedipine1件: D00437 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81
208 Nitroglycerin
(Synonym: Apo-nitroglycerin)		2件: Nitroglycerin; Nitroglycerine1件: D00515 --2件: 46, 51
209 Nortriptyline
(Synonym: Apo-nortriptyline - Cap 25mg)		2件: Nortriptyline; Nortriptyline hydrochloride1件: D08288 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226
210 Olanzapine
(Synonym: Olanzapine Apotex)		2件: Olanzapine; Zyprexa1件: D00454 11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8
211 Olive oil
(Synonym: Rhodd Ato Repair Body So Ap)		1件: Olive Oil1件: D03311 --5件: 13, 35, 49, 53, 162
212 Omeprazole
(Synonym: Not Applicable)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
213 Ondansetron
(Synonym: Apo-ondansetron)		1件: Ondansetron1件: D00456 5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬3件: 6, 97, 107
214 Oxcarbazepine
(Synonym: Apo-oxcarbazepine)		2件: Oxcarbazepine; Trileptal1件: D00533 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 13
215 Oxybutynin
(Synonym: Apo-oxybutynin)		1件: Oxybutynin1件: D00465 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
216 Oxycodone
(Synonym: Oxycodone Apap)		2件: OXYCODONE; OXYCODONE HYDROCHLORIDE1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
217 Paclitaxel
(Synonym: Apealea)		1件: Paclitaxel1件: D00491 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬2件: 46, 85
218 Pantoprazole
(Synonym: Apo-pantoprazole)		1件: PANTOPRAZOLE1件: D05353 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 13, 65
219 Paroxetine
(Synonym: Apo-paroxetine)		1件: Paroxetine1件: D02362 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
220 Pectin
(Synonym: SMITH BROS WARM APPLE PIE WITH CINNAMON FLAVOR Warming Throat)		1件: Pectin1件: D02316 --1件: 96
221 Pegfilgrastim
(Synonym: pegfilgrastim-apgf)		1件: Pegfilgrastim1件: D06889 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 60
222 Perindopril
(Synonym: Apo-perindopril-indapamide)		2件: Coversyl; Perindopril1件: D03753 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222
223 Petrolatum
(Synonym: Apj Hemorrhoidal)		1件: Petrolatum1件: D05331 --1件: 158
224 Phenoxymethylpenicillin
(Synonym: Apo Pen Vk)		0件: 1件: D05411 --1件: 97
225 Phenylephrine
(Synonym: Apz Hemorrhoidal Suppositories)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
226 Pioglitazone
(Synonym: Apo-pioglitazone)		1件: Pioglitazone1件: D08378 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
227 Posaconazole
(Synonym: Apo-posaconazole)		2件: Noxafil; Posaconazole1件: D02555 --3件: 60, 65, 299
228 Pramipexole
(Synonym: Apo-pramipexole)		7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL1件: D05575 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
229 Pravastatin
(Synonym: Apo-pravastatin)		2件: Pravastatin; Pravastatin sodium1件: D08410 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333
230 Prednisone
(Synonym: Apo Prednisone Tab 5mg)		3件: PREDNISONA; Prednisone; RAYOS1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
231 Pregabalin
(Synonym: Apo-pregabalin Capsules)		2件: Lyrica; Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
232 Propranolol
(Synonym: Apo-propranolol)		2件: Propanolol; Propranolol1件: D08443 3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 158, 167, 227, 278, 296
233 Prucalopride
(Synonym: Apo-prucalopride)		2件: Prucalopride; Resolor1件: D09205 1件: HTR4 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬3件: 13, 51, 96
234 Pseudoephedrine
(Synonym: Aprodine)		1件: Pseudoephedrine1件: D08449 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
235 Pyridoxine
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		2件: Pyridoxine; Vitamin B61件: D08454 --5件: 6, 93, 145, 206, 320
236 Quetiapine
(Synonym: Apo-quetiapine XR)		2件: Quetiapine; Seroquel1件: D08456 2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13
237 Quinapril
(Synonym: Apo-quinapril/hctz)		1件: Accuretic1件: D03752 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 19
238 Quinidine
(Synonym: Apo Quinidine Tab 200mg)		4件: Nuedexta; Quinidina; Quinidine; Quinidine Sulfate1件: D08458 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 2, 8, 13
239 Quinine
(Synonym: Apo-quinine)		0件: 2件: D08460 ,
D08461 		--1件: 6
240 Rabeprazole
(Synonym: Apo-rabeprazole)		1件: Rabeprazole1件: D08463 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 2, 51
241 Raloxifene
(Synonym: Apo-raloxifene)		2件: Raloxifene; Raloxifene hydrochloride1件: D08465 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 46
242 Ramipril
(Synonym: Apo-ramipril/hctz)		1件: Ramipril1件: D00421 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257
243 Ranitidine
(Synonym: Apo-ranitidine)		1件: Ranitidine1件: D00422 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 13, 65
244 Rasagiline
(Synonym: Apo-rasagiline)		4件: Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE2件: D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬6件: 2, 5, 6, 17, 58, 66
245 Repaglinide
(Synonym: Apo-repaglinide)		1件: Repaglinide1件: D00594 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299
246 Riboflavin
(Synonym: Appedrine)		2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
247 Riluzole
(Synonym: Apo-riluzole)		2件: Rilutek; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
248 Risedronic acid
(Synonym: Apo-risedronate Dr)		3件: Risedronate; RISEDRONATE SODIUM; Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
249 Risperidone
(Synonym: Apo-risperidone)		1件: Risperidone1件: D00426 2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬5件: 8, 156, 179, 187, 206
250 Rivastigmine
(Synonym: Apo-rivastigmine)		3件: EXELON; RIVASTIGMINE; Rivastigmine Transdermal System1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
251 Ropinirole
(Synonym: Apo-ropinirole)		3件: REQUIP; Ropinirole; Ropinirole Hydrochloride1件: D08489 3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 74, 309
252 Rosuvastatin
(Synonym: Apo-rosuvastatin)		3件: Crestor; Rosuvastatin; Rosuvastatin calcium1件: D08492 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
253 Royal jelly
(Synonym: Apis Mellifera Secretion)		1件: Royal jelly1件: D09754 --1件: 49
254 Salbutamol
(Synonym: Apo-salvent Tablets - 2mg)		3件: Albuterol; Salbutamol; Ventolin1件: D02147 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
255 Salicylic acid
(Synonym: Classic Care Apricot Scrub Blemish Control)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
256 Saxagliptin
(Synonym: Apo-saxagliptin)		1件: Saxagliptin1件: D08996 1件: DPP4 💬1件: Protein digestion and absorption 💬1件: 299
257 Sertraline
(Synonym: Apo-sertraline)		1件: Sertraline1件: D02360 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
258 Sildenafil
(Synonym: Apo-sildenafil R)		6件: Mysildecard; REVATIO; Sildenafil; Sildenafil citrate; SILDENAFILO; VIAGRA1件: D08514 (Name: Aphrodil (TN))1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
259 Silodosin
(Synonym: Apo-silodosin)		2件: Silodosin; Silodyx1件: D01965 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
260 Simvastatin
(Synonym: Apo-simvastatin)		3件: Simvastatin; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
261 Sitagliptin
(Synonym: Apo-sitagliptin/metformin XR)		1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
262 Sodium bicarbonate
(Synonym: Not Applicable)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
263 Sodium chloride
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		6件: Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; SPORANOX1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
264 Sodium fluoride
(Synonym: Pcxx Grape Apf G)		1件: Sodium fluoride1件: D00943 --1件: 51
265 Solifenacin
(Synonym: Apo-solifenacin)		2件: Solifenacin; Solifenacin Succinate1件: D08522 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
266 Sorafenib
(Synonym: Apo-sorafenib)		2件: Nexavar; Sorafenib1件: D08524 8件: BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 34, 86
267 Spironolactone
(Synonym: Apo-spirozide Tab)		1件: Spironolactone1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225
268 Streptococcus pneumoniae type 1 capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
269 Streptococcus pneumoniae type 10a capsular polysaccharide antigen
(Synonym: Apexxnar)		1件: Pneumovax 23---2件: 46, 50
270 Streptococcus pneumoniae type 11a capsular polysaccharide antigen
(Synonym: Apexxnar)		1件: Pneumovax 23---2件: 46, 50
271 Streptococcus pneumoniae type 12f capsular polysaccharide antigen
(Synonym: Apexxnar)		1件: Pneumovax 23---2件: 46, 50
272 Streptococcus pneumoniae type 14 capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
273 Streptococcus pneumoniae type 15b capsular polysaccharide antigen
(Synonym: Apexxnar)		1件: Pneumovax 23---2件: 46, 50
274 Streptococcus pneumoniae type 18c capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
275 Streptococcus pneumoniae type 19a capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
276 Streptococcus pneumoniae type 19f capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
277 Streptococcus pneumoniae type 23f capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
278 Streptococcus pneumoniae type 4 capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
279 Streptococcus pneumoniae type 5 capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
280 Streptococcus pneumoniae type 6b capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
281 Streptococcus pneumoniae type 7f capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
282 Streptococcus pneumoniae type 8 capsular polysaccharide antigen
(Synonym: Apexxnar)		1件: Pneumovax 23---2件: 46, 50
283 Streptococcus pneumoniae type 9v capsular polysaccharide antigen
(Synonym: Apexxnar)		2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222
284 Sucralfate
(Synonym: Apo-sucralfate - Tab 1g)		1件: Sucralfate1件: D00446 --1件: 98
285 Sulfamethoxazole
(Synonym: Apo-sulfatrim Oral Suspension)		3件: Bactrim; Sulfamethoxazole; Sulphamethoxazole1件: D00447 --5件: 44, 49, 61, 85, 299
286 Sulfasalazine
(Synonym: Apo Sulfasalazine Tab 500mg)		3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine1件: D00448 --6件: 46, 86, 94, 107, 270, 271
287 Sulindac
(Synonym: Apo-sulin Tab 200mg)		1件: Sulindac1件: D00120 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206
288 Tacrolimus
(Synonym: Apo-tacrolimus)		2件: Prograf; TACROLIMUS2件: D00107 ,
D08556 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
289 Tadalafil
(Synonym: Apo-tadalafil)		4件: Adcirca; Cialis; Tadalafil; TADALAFILO1件: D02008 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
290 Tamoxifen
(Synonym: Apo-tamox Tab 10mg)		2件: TAMOXIFEN; TAMOXIFEN CITRATE1件: D08559 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬3件: 2, 113, 227
291 Tamsulosin
(Synonym: Apo-tamsulosin CR)		1件: Tamsulosin1件: D08560 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13
292 Telmisartan
(Synonym: Apo-telmisartan)		1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
293 Temozolomide
(Synonym: Apo-temozolomide)		1件: Temozolomide1件: D06067 --1件: 34
294 Tenofovir disoproxil
(Synonym: Apo-tenofovir)		4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---2件: 93, 265
295 Terazosin
(Synonym: Apo-terazosin)		1件: Terazosin1件: D08569 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
296 Terbinafine
(Synonym: Apo-terbinafine)		1件: Terbinafine1件: D02375 --3件: 96, 97, 271
297 Teriflunomide
(Synonym: Apo-teriflunomide)		2件: AUBAGIO; TERIFLUNOMIDE1件: D10172 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬3件: 13, 25, 26
298 Teriparatide
(Synonym: Apo-teriparatide Injection)		4件: Forsteo; Forteo; PTH 1-34; Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬7件: 46, 65, 68, 70, 71, 235, 274
299 Tetrabenazine
(Synonym: Apo-tetrabenazine)		2件: Tetrabenazine; Xenazine1件: D08575 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
300 Tetracycline
(Synonym: APT T3X Tetracycline Hydrochloride First Aid Antibiotic)		2件: Tetracyclin; Tetracycline1件: D00201 --5件: 13, 36, 46, 53, 97
301 Theophylline
(Synonym: Apo-theo ER)		1件: Theophylline2件: D00371 ,
D06103 		18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299
302 Thiamine
(Synonym: Appedrine)		2件: THIAMINE; Vitamin B11件: D08580 --4件: 8, 93, 145, 265
303 Ticagrelor
(Synonym: Apo-ticagrelor)		1件: Ticagrelor1件: D09017 1件: P2RY12 💬1件: Platelet activation 💬3件: 36, 46, 85
304 Timolol
(Synonym: Apo-travoprost-timop Pq)		2件: Timolol; TIMOLOL MALEATE2件: D00378 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
305 Tipranavir
(Synonym: Aptivus)		1件: Tipranavir1件: D08605 (Name: Aptivus (TN))--1件: 265
306 Tobramycin
(Synonym: Apo-tobramycin)		9件: Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum1件: D00063 --1件: 299
307 Tolterodine
(Synonym: Apo-tolterodine)		1件: Tolterodine1件: D00646 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53
308 Topiramate
(Synonym: Apo-topiramate)		2件: TOPAMAX; Topiramate1件: D00537 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
309 Tramadol
(Synonym: Apo-tramadol/acet)		2件: Tramadol; Ultracet1件: D08623 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
310 Trazodone
(Synonym: Apo-trazodone Tablets 50mg)		1件: Trazodone1件: D08626 4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 2
311 Triamcinolone
(Synonym: Apo-triamcinolone AQ)		4件: Kenalog; Naltrexone; TRIAMCINOLONE; Triamcinolone Acetonide1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
312 Trifluoperazine 1件: Trifluoperazine2件: D01448 ,
D08636 (Name: Apo-trifluoperazine (TN))		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284
313 Trihexyphenidyl
(Synonym: Aparkane Tab 2mg)		1件: Trihexyphenidyl1件: D08638 (Name: Apo-trihex (TN))5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
314 Trimethoprim
(Synonym: Apo-sulfatrim Oral Suspension)		2件: Bactrim; TRIMETHOPRIM1件: D00145 --8件: 36, 44, 49, 60, 61, 85, 298, 299
315 Tryptophan
(Synonym: Apo-tryptophan)		2件: Propanoic acid; Tryptophan1件: D00020 --2件: 6, 75
316 Tyrosine
(Synonym: Appformin-D)		4件: Alanine; L-Tyrosine; Propanoic acid; Tyrosine1件: D00022 --5件: 6, 75, 86, 111, 298
317 Urea
(Synonym: Not Applicable)		1件: Urea2件: D00023 ,
D01749 		--2件: 72, 251
318 Valaciclovir
(Synonym: Apo-valacyclovir)		1件: Valacyclovir2件: D08664 ,
D10518 		--1件: 65
319 Valganciclovir
(Synonym: Apo-valganciclovir)		1件: Valganciclovir1件: D02495 --4件: 85, 97, 299, 331
320 Valproic acid
(Synonym: Apo-valproic Acid)		3件: Valproate; VALPROATE SODIUM; Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
321 Valsartan
(Synonym: Apo-valsartan)		3件: Diovan; Entresto; Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224
322 Vardenafil
(Synonym: Apo-vardenafil)		3件: Levitra; Vardenafil; Vardenafilo1件: D08668 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬3件: 13, 86, 299
323 Varenicline
(Synonym: Apo-varenicline)		2件: Champix; Varenicline1件: D08669 2件: CHRNA4,
CHRNB2 💬		4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬3件: 6, 18, 53
324 Venlafaxine
(Synonym: Apo-venlafaxine XR)		2件: Venlafaxine; VENLAFAXINE HYDROCHLORIDE1件: D08670 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 13, 46
325 Verapamil
(Synonym: Apo-verap Tab 80mg)		3件: VERAPAMIL; VERAPAMIL HYDROCHLORIDE; Verapamil SR1件: D02356 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 58, 96, 140, 167
326 Vitamin A
(Synonym: Appedrine)		1件: Vitamin A1件: D06543 2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
327 Vitamin D
(Synonym: Appedrine)		3件: Calciferol; Cod liver oil; Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
328 Voriconazole
(Synonym: Apo-voriconazole)		2件: Vfend; VORICONAZOLE1件: D00578 --2件: 60, 299
329 Warfarin
(Synonym: Apo-warfarin)		2件: Warfarin; Warfarin Sodium1件: D08682 2件: NQO1,
VKORC1 💬		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
330 Zidovudine
(Synonym: Apo-abacavir-lamivudine-zidovudine)		3件: COMBIVIR; Retrovir; Zidovudine1件: D00413 --7件: 25, 26, 94, 135, 265, 325, 331
331 Zinc
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		3件: Nicotinamide; Wilzin; Zinc---4件: 2, 113, 171, 299
332 Zinc oxide
(Synonym: Lbel Clarite Makeup Foundation for A Clearer Appearance SPF 30 240-C)		1件: Zinc oxide1件: D01170 --1件: 156
333 Zolmitriptan
(Synonym: Apo-zolmitriptan Rapid)		1件: Zolmitriptan1件: D00415 2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
334 Zolpidem
(Synonym: Apo-zolpidem ODT)		2件: Zolpidem; Zolpidem Tartrate1件: D08690 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46
335 Zopiclone
(Synonym: Apo-zopiclone)		1件: Zopiclone1件: D01372 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6