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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
TNFSF13B
💬
1. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
[4]
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Belimumab
Belimumab
💬
1. TNFSF13B
×
Name
Other Names
Belimumab
Belimumab (USAN)
Belimumab (genetical recombination) (JAN)
Benlysta (TN)
LymphoStat-B (TN)
Belimumab
[13]
11
11
,
13
,
43
,
44
,
46
,
49
,
51
,
53
,
63
,
66
,
222
,
296
,
300
💬
1. TNFSF13B
×
Disease ID
Name
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
43
Microscopic polyangiitis
44
Wegener granulomatosis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
53
Sjogren syndrome
63
Idiopathic thrombocytopenic purpura
66
IgA nephropathy
222
Primary nephrotic syndrome
296
Biliary atresia
300
IgG4-related disease
2
TNFSF13B
💬
2. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
[4]
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Atacicept
Atacicept
💬
2. TNFSF13B
×
Name
Other Names
Atacicept
Atacicept (USAN/INN)
Atacicept
[4]
13
13
,
46
,
49
,
66
💬
2. TNFSF13B
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
66
IgA nephropathy
3
TNFSF13B
💬
3. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
[4]
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tabalumab
Tabalumab
💬
3. TNFSF13B
×
Name
Other Names
Tabalumab
Tabalumab (USAN)
Tabalumab (genetical recombination) (JAN)
Tabalumab
[2]
46
46
,
49
💬
3. TNFSF13B
×
Disease ID
Name
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
4
TNFSF13B
💬
4. TNFSF13B
×
Name
Full Name
TNFSF13B
TNF superfamily member 13b
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Rheumatoid arthritis
[4]
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Tibulizumab
Tibulizumab
💬
4. TNFSF13B
×
Name
Other Names
Tibulizumab
Tibulizumab (USAN/INN)
Tibulizumab
[1]
53
53
💬
4. TNFSF13B
×
Disease ID
Name
53
Sjogren syndrome
5
TNFRSF13C
💬
5. TNFRSF13C
×
Name
Full Name
TNFRSF13C
TNF receptor superfamily member 13C
[5]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network for IgA production
,
Human T-cell leukemia virus 1 infection
,
Primary immunodeficiency
[5]
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Intestinal immune network
...
Ianalumab
Ianalumab
💬
5. TNFRSF13C
×
Name
Other Names
Ianalumab
Ianalumab (USAN/INN)
Ianalumab
[7]
35
35
,
46
,
49
,
53
,
61
,
63
,
95
💬
5. TNFRSF13C
×
Disease ID
Name
35
Pemphigus
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
53
Sjogren syndrome
61
Autoimmune hemolytic anemia
63
Idiopathic thrombocytopenic purpura
95
Autoimmune hepatitis
6
PARP1
💬
6. PARP1
×
Name
Full Name
PARP1
poly(ADP-ribose) polymerase 1
[5]
Base excision repair
Base excision repair
,
NF-kappa B signaling pathway
,
Apoptosis
,
Necroptosis
,
Diabetic cardiomyopathy
[5]
Base excision repair
,
NF-kappa B signaling pathway
,
Apoptosis
,
Necroptosis
,
Diabetic cardiomyopa
...
Olaparib
Olaparib
💬
6. PARP1
×
Name
Other Names
Olaparib
Olaparib (JAN/USAN/INN)
Lynparza (TN)
Olaparib
[2]
86
86
,
285
💬
6. PARP1
×
Disease ID
Name
86
Pulmonary arterial hypertension
285
Fanconi anemia
7
IL1B
💬
7. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
[44]
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[44]
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Pirfenidone
Pirfenidone
💬
7. IL1B
×
Name
Other Names
Pirfenidone
Pirfenidone (JAN/USAN/INN)
Esbriet (TN)
Pirfenidone
[11]
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
💬
7. IL1B
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
50
Dermatomyositis
51
Scleroderma
58
Hypertrophic cardiomyopathy
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
164
Oculocutaneous albinism
222
Primary nephrotic syndrome
228
Bronchiolitis obliterans
8
IL1B
💬
8. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
[44]
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[44]
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Rilonacept
Rilonacept
💬
8. IL1B
×
Name
Other Names
Rilonacept
Rilonacept (USAN/INN)
Arcalyst (TN)
Rilonacept
[4]
51
51
,
106
,
107
,
266
💬
8. IL1B
×
Disease ID
Name
51
Scleroderma
106
Cryopyrin-associated periodic syndrome
107
Juvenile idiopathic arthritis
266
Familial mediterranean fever
9
IL1B
💬
9. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
[44]
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[44]
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Canakinumab
Canakinumab
💬
9. IL1B
×
Name
Other Names
Canakinumab
Canakinumab (USAN/INN)
Canakinumab (genetical recombination) (JAN)
Ilaris (TN)
Canakinumab
[10]
46
46
,
56
,
84
,
106
,
107
,
108
,
113
,
266
,
267
,
269
💬
9. IL1B
×
Disease ID
Name
46
Malignant rheumatoid arthritis
56
Behcet disease
84
Sarcoidosis
106
Cryopyrin-associated periodic syndrome
107
Juvenile idiopathic arthritis
108
TNF receptor-associated periodic syndrome
113
Muscular dystrophy
266
Familial mediterranean fever
267
Hyper-IgD syndrome
269
Pyogenic arthritis
10
IL1B
💬
10. IL1B
×
Name
Full Name
IL1B
interleukin 1 beta
[44]
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa B signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th17 cell differentiation
,
TNF signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Inflammatory bowel disease
,
Rheumatoid arthritis
,
Graft-versus-host disease
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[44]
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
NF-kappa
...
Gevokizumab
Gevokizumab
💬
10. IL1B
×
Name
Other Names
Gevokizumab
Gevokizumab (USAN/INN)
Gevokizumab
[4]
41
41
,
50
,
56
,
269
💬
10. IL1B
×
Disease ID
Name
41
Giant cell arteritis
50
Dermatomyositis
56
Behcet disease
269
Pyogenic arthritis