Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

2

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

3

[16] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...

[1] 46 💬

4

[4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...

Omalizumab 💬

[7] 46, 53, 65, 98, 162, 226, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
53	Sjogren syndrome
65	Primary immunodeficiency
98	Eosinophilic gastrointestinal disease
162	Pemphigoid
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

5

[6] Arachidonic acid metabolism, Metabolic pathways, Fc epsilon RI signaling pathway, Serotonergic s ...

[3] 85, 160, 164 💬

6

[6] Arachidonic acid metabolism, Metabolic pathways, Fc epsilon RI signaling pathway, Serotonergic s ...

[1] 113 💬

7

[14] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, Osteoclast di ...

[2] 51, 85 💬

8

[14] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, Osteoclast di ...

[2] 51, 85 💬

9

[16] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...

Binetrakin 💬

[1] 46 💬

10

[13] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...

Mepolizumab 💬

[4] 44, 45, 98, 162 💬

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