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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

CYSLTR1 💬

[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction

Montelukast 💬

Montelukast

[8] 6, 13, 46, 61, 63, 85, 98, 228 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
85	Idiopathic interstitial pneumonia
98	Eosinophilic gastrointestinal disease
228	Bronchiolitis obliterans

AGTR1 💬

[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...

Losartan 💬

Losartan

[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

Disease ID	Name
17	Multiple system atrophy
19	Lysosomal storage disease
36	Epidermolysis bullosa
58	Hypertrophic cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastrointestinal disease
113	Muscular dystrophy
164	Oculocutaneous albinism
167	Marfan syndrome
179	Williams syndrome
215	Tetralogy of Fallot
222	Primary nephrotic syndrome
299	Cystic fibrosis

S1PR1 💬

[3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

Etrasimod 💬

Etrasimod

[3] 96, 97, 98 💬

S1PR3 💬

[2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

Etrasimod 💬

Etrasimod

[3] 96, 97, 98 💬

FCER1A 💬

[4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...

Omalizumab 💬

Omalizumab

[7] 46, 53, 65, 98, 162, 226, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
53	Sjogren syndrome
65	Primary immunodeficiency
98	Eosinophilic gastrointestinal disease
162	Pemphigoid
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

MTOR 💬

[51] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...

Sirolimus 💬

Sirolimus

[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...

Disease ID	Name
2	Amyotrophic lateral sclerosis
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
17	Multiple system atrophy
19	Lysosomal storage disease
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
96	Crohn disease
98	Eosinophilic gastrointestinal disease
137	Focal cortical dysplasia
157	Sturge-Weber syndrome
158	Tuberous sclerosis
192	Cockayne syndrome
193	Prader-Willi syndrome
222	Primary nephrotic syndrome
256	Muscle glycogenosis
277	Lymphangiomatosis
278	Huge lymphatic malformation with cervicofacial lesion
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
280	Huge arteriovenous malformation with cervicofacial or limb lesion
281	Klippel-Trenaunay-Weber syndrome
283	Acquired pure red cell aplasia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

GABRA1 💬

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Propofol 💬

Propofol

[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬

Disease ID	Name
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
75	Cushing disease
98	Eosinophilic gastrointestinal disease
296	Biliary atresia

GABRA2 💬

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Propofol 💬

Propofol

[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬

Disease ID	Name
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
75	Cushing disease
98	Eosinophilic gastrointestinal disease
296	Biliary atresia

GABRA3 💬

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Propofol 💬

Propofol

[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬

Disease ID	Name
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
75	Cushing disease
98	Eosinophilic gastrointestinal disease
296	Biliary atresia

GABRA4 💬

[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...

Propofol 💬

Propofol

[9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬

Disease ID	Name
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
75	Cushing disease
98	Eosinophilic gastrointestinal disease
296	Biliary atresia

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