Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 71 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
CD52
💬1. CD52
| - | Alemtuzumab
Alemtuzumab
💬1. CD52
| Alemtuzumab | [22] 13 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬1. CD52
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| 2 |
TPP1
💬2. TPP1
| [1] Lysosome Lysosome | Cerliponase alfa
Cerliponase alfa
💬2. TPP1
| Cerliponase alfa | [1] 19 19 💬2. TPP1
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| 3 |
CSF3R
💬3. CSF3R
| [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ... | Lenograstim
Lenograstim
💬3. CSF3R
| Lenograstim | [7] 2 2, 13, 16, 18, 19, 57, 65 💬
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| 4 |
ACE
💬4. ACE
| [6] Renin-angiotensin system Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ... | Lisinopril
Lisinopril
💬4. ACE
| Lisinopril | [7] 19 19, 46, 49, 66, 67, 113, 222 💬
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| 5 |
ACE
💬5. ACE
| [6] Renin-angiotensin system Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ... | Quinapril
Quinapril
💬5. ACE
| Quinapril | [1] 19 19 💬5. ACE
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| 6 |
ACE
💬6. ACE
| [6] Renin-angiotensin system Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ... | Enalapril
Enalapril
💬6. ACE
| Enalapril | [6] 19 19, 46, 66, 113, 210, 222 💬
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| 7 |
ACE
💬7. ACE
| [6] Renin-angiotensin system Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ... | Lisinopril
Lisinopril
💬7. ACE
| Lisinopril | [7] 19 19, 46, 49, 66, 67, 113, 222 💬
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| 8 |
DHFR
💬8. DHFR
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬8. DHFR
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 8. DHFR
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| 9 |
NQO1
💬9. NQO1
| [7] Ubiquinone and other terpenoid-quinone biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofacto ... | Warfarin
Warfarin
💬9. NQO1
| Warfarin | [11] 6 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬9. NQO1
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| 10 |
AGTR1
💬10. AGTR1
| [16] Calcium signaling pathway Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy [16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ... | Angiotensin II
Angiotensin II
💬10. AGTR1
| Angiotensin II | [7] 17 17, 19, 46, 66, 86, 222, 224 💬
|