DDrare
Disease
Drug
Target Gene/Pathway
Contact
JA
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 59 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
ADRA1D
💬
1. ADRA1D
×
Name
Full Name
ADRA1D
adrenoceptor alpha 1D
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Doxazosin
Doxazosin
💬
1. ADRA1D
×
Name
Other Names
Doxazosin
Doxazosin (INN)
Cardura XL (TN)
Doxazosin
[2]
57
57
,
67
💬
1. ADRA1D
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
67
Polycystic kidney disease
2
ADRA1B
💬
2. ADRA1B
×
Name
Full Name
ADRA1B
adrenoceptor alpha 1B
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[6]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Doxazosin
Doxazosin
💬
2. ADRA1B
×
Name
Other Names
Doxazosin
Doxazosin (INN)
Cardura XL (TN)
Doxazosin
[2]
57
57
,
67
💬
2. ADRA1B
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
67
Polycystic kidney disease
3
ADRA1A
💬
3. ADRA1A
×
Name
Full Name
ADRA1A
adrenoceptor alpha 1A
[7]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
,
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Salivary secretion
[7]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
, ...
Doxazosin
Doxazosin
💬
3. ADRA1A
×
Name
Other Names
Doxazosin
Doxazosin (INN)
Cardura XL (TN)
Doxazosin
[2]
57
57
,
67
💬
3. ADRA1A
×
Disease ID
Name
57
Idiopathic dilated cardiomyopathy
67
Polycystic kidney disease
4
ADRB1
💬
4. ADRB1
×
Name
Full Name
ADRB1
adrenoceptor beta 1
[11]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Gap junction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
[11]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive liga
...
Bisoprolol
Bisoprolol
💬
4. ADRB1
×
Name
Other Names
Bisoprolol
Bisoprolol (JAN/USAN/INN)
Bisoprolol
[4]
58
58
,
67
,
86
,
113
💬
4. ADRB1
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
67
Polycystic kidney disease
86
Pulmonary arterial hypertension
113
Muscular dystrophy
5
ACE
💬
5. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
[6]
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
[6]
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Lisinopril
Lisinopril
💬
5. ACE
×
Name
Other Names
Lisinopril
Lisinopril (USP)
Lisinopril hydrate (JP18)
Lisinopril dihydrate
Prinivil (TN)
Zestril (TN)
QBRELIS
LISINORIL
Lisinopril
[7]
19
19
,
46
,
49
,
66
,
67
,
113
,
222
💬
5. ACE
×
Disease ID
Name
19
Lysosomal storage disease
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
66
IgA nephropathy
67
Polycystic kidney disease
113
Muscular dystrophy
222
Primary nephrotic syndrome
6
ACE
💬
6. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
[6]
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
[6]
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Ramipril
Ramipril
💬
6. ACE
×
Name
Other Names
Ramipril
Ramipril (USP/INN)
Altace (TN)
Ramipril
[7]
46
46
,
49
,
66
,
67
,
113
,
218
,
257
💬
6. ACE
×
Disease ID
Name
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
66
IgA nephropathy
67
Polycystic kidney disease
113
Muscular dystrophy
218
Alport syndrome
257
Hepatic glycogenosis
7
ACE
💬
7. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
[6]
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
[6]
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Imidapril
Imidapril
💬
7. ACE
×
Name
Other Names
Imidapril
Imidapril (INN)
Hipertene (TN)
Imidapril
[1]
67
67
💬
7. ACE
×
Disease ID
Name
67
Polycystic kidney disease
8
ACE
💬
8. ACE
×
Name
Full Name
ACE
angiotensin I converting enzyme
[6]
Renin-angiotensin system
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hypertrophic cardiomyopathy
,
Diabetic cardiomyopathy
[6]
Renin-angiotensin system
,
Renin secretion
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Hyper
...
Lisinopril
Lisinopril
💬
8. ACE
×
Name
Other Names
Lisinopril
Lisinopril (INN)
Zestril (TN)
Lisinopril
[7]
19
19
,
46
,
49
,
66
,
67
,
113
,
222
💬
8. ACE
×
Disease ID
Name
19
Lysosomal storage disease
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
66
IgA nephropathy
67
Polycystic kidney disease
113
Muscular dystrophy
222
Primary nephrotic syndrome
9
AGTR1
💬
9. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Candesartan
Candesartan
💬
9. AGTR1
×
Name
Other Names
Candesartan
Candesartan (USAN/INN)
Candesartan
[2]
58
58
,
67
💬
9. AGTR1
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
67
Polycystic kidney disease
10
AGTR1
💬
10. AGTR1
×
Name
Full Name
AGTR1
angiotensin II receptor type 1
[16]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Vascular smooth muscle contraction
,
Apelin signaling pathway
,
Renin-angiotensin system
,
Renin secretion
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Diabetic cardiomyopathy
[16]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
Phospholipase D signaling pathway
,
Neuro
...
Candesartan cilexetil
Candesartan cilexetil
💬
10. AGTR1
×
Name
Other Names
Candesartan cilexetil
Candesartan cilexetil (JP18/USP)
Atacand (TN)
CANDESARTAN
Candesartan cilexetil
[1]
67
67
💬
10. AGTR1
×
Disease ID
Name
67
Polycystic kidney disease