Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

2

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

3

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Chlorpromazine 💬

[1] 254 💬

4

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Diphenhydramine 💬

Diphenhydramine

[8] 11, 13, 49, 51, 70, 86, 222, 256 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
51	Scleroderma
70	Spinal stenosis
86	Pulmonary arterial hypertension
222	Primary nephrotic syndrome
256	Muscle glycogenosis

5

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Loratadine 💬

[4] 13, 46, 89, 98 💬

6

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Olanzapine 💬

[2] 2, 8 💬

7

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Promethazine 💬

[1] 96 💬

8

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Clemastine 💬

[1] 13 💬

9

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Desloratadine 💬

[1] 13 💬

10

[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regula ...

Chlorphenamine 💬

Chlorpheniramine

[1] 14 💬

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