Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[5] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...

Mogamulizumab 💬

[1] 26 💬

2

[11] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Cytokine-cytokine receptor int ...

[2] 46, 84 💬

3

[11] Viral life cycle - HIV-1, Virion - Human immunodeficiency virus, Cytokine-cytokine receptor int ...

Cenicriviroc 💬

[1] 94 💬

4

[6] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...

[2] 298, 299 💬

5

[7] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...

[2] 298, 299 💬

6

[24] EGFR tyrosine kinase inhibitor resistance, Chemokine signaling pathway, PI3K-Akt signaling path ...

Ruxolitinib 💬

[3] 60, 65, 228 💬

7

[24] EGFR tyrosine kinase inhibitor resistance, Chemokine signaling pathway, PI3K-Akt signaling path ...

Tofacitinib 💬

[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬

Disease ID	Name
11	Myasthenia gravis
40	Takayasu arteritis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
65	Primary immunodeficiency
84	Sarcoidosis
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
271	Ankylosing spondylitis
300	IgG4-related disease

8

[24] EGFR tyrosine kinase inhibitor resistance, Chemokine signaling pathway, PI3K-Akt signaling path ...

Baricitinib 💬

[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
93	Primary biliary cholangitis
107	Juvenile idiopathic arthritis
162	Pemphigoid
265	Lipodystrophy
269	Pyogenic arthritis
325	Hereditary autoinflammatory syndrome

9

[24] EGFR tyrosine kinase inhibitor resistance, Chemokine signaling pathway, PI3K-Akt signaling path ...

Peficitinib 💬

[1] 46 💬

10

[15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regula ...

Tofacitinib 💬

[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬

Disease ID	Name
11	Myasthenia gravis
40	Takayasu arteritis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
65	Primary immunodeficiency
84	Sarcoidosis
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
271	Ankylosing spondylitis
300	IgG4-related disease

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