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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
ADH1A
💬
1. ADH1A
×
Name
Full Name
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
[9]
Glycolysis / Gluconeogenesis
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
,
Retinol metabolism
,
Metabolism of xenobiotics by cytochrome P450
,
Drug metabolism - cytochrome P450
,
Metabolic pathways
,
Alcoholic liver disease
[9]
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
, ...
Fomepizole
Fomepizole
💬
1. ADH1A
×
Name
Other Names
Fomepizole
Fomepizole (JAN/USAN/INN)
Antizol (TN)
Fomepizole
[1]
301
301
💬
1. ADH1A
×
Disease ID
Name
301
Macular dystrophy
2
ADH1B
💬
2. ADH1B
×
Name
Full Name
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
[9]
Glycolysis / Gluconeogenesis
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
,
Retinol metabolism
,
Metabolism of xenobiotics by cytochrome P450
,
Drug metabolism - cytochrome P450
,
Metabolic pathways
,
Alcoholic liver disease
[9]
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
, ...
Fomepizole
Fomepizole
💬
2. ADH1B
×
Name
Other Names
Fomepizole
Fomepizole (JAN/USAN/INN)
Antizol (TN)
Fomepizole
[1]
301
301
💬
2. ADH1B
×
Disease ID
Name
301
Macular dystrophy
3
CPT1C
💬
3. CPT1C
×
Name
Full Name
CPT1C
carnitine palmitoyltransferase 1C
[8]
Fatty acid degradation
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
,
Thermogenesis
,
Adipocytokine signaling pathway
,
Glucagon signaling pathway
,
Alcoholic liver disease
[8]
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
,
T
...
Perhexiline
Perhexiline
💬
3. CPT1C
×
Name
Other Names
Perhexiline
Perhexiline (INN)
Perhexiline
[2]
58
58
,
272
💬
3. CPT1C
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
272
Fibrodysplasia ossificans progressiva
4
ADH1C
💬
4. ADH1C
×
Name
Full Name
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
[9]
Glycolysis / Gluconeogenesis
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
,
Retinol metabolism
,
Metabolism of xenobiotics by cytochrome P450
,
Drug metabolism - cytochrome P450
,
Metabolic pathways
,
Alcoholic liver disease
[9]
Glycolysis / Gluconeogenesis
,
Fatty acid degradation
,
Tyrosine metabolism
,
Pyruvate metabolism
, ...
Fomepizole
Fomepizole
💬
4. ADH1C
×
Name
Other Names
Fomepizole
Fomepizole (JAN/USAN/INN)
Antizol (TN)
Fomepizole
[1]
301
301
💬
4. ADH1C
×
Disease ID
Name
301
Macular dystrophy
5
CPT1A
💬
5. CPT1A
×
Name
Full Name
CPT1A
carnitine palmitoyltransferase 1A
[9]
Fatty acid degradation
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
,
Thermogenesis
,
Adipocytokine signaling pathway
,
Glucagon signaling pathway
,
Insulin resistance
,
Alcoholic liver disease
[9]
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
,
T
...
Perhexiline
Perhexiline
💬
5. CPT1A
×
Name
Other Names
Perhexiline
Perhexiline (INN)
Perhexiline
[2]
58
58
,
272
💬
5. CPT1A
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
272
Fibrodysplasia ossificans progressiva
6
CPT1B
💬
6. CPT1B
×
Name
Full Name
CPT1B
carnitine palmitoyltransferase 1B
[10]
Fatty acid degradation
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
,
Thermogenesis
,
Adipocytokine signaling pathway
,
Glucagon signaling pathway
,
Insulin resistance
,
Alcoholic liver disease
,
Diabetic cardiomyopathy
[10]
Fatty acid degradation
,
Fatty acid metabolism
,
PPAR signaling pathway
,
AMPK signaling pathway
, ...
Perhexiline
Perhexiline
💬
6. CPT1B
×
Name
Other Names
Perhexiline
Perhexiline (INN)
Perhexiline
[2]
58
58
,
272
💬
6. CPT1B
×
Disease ID
Name
58
Hypertrophic cardiomyopathy
272
Fibrodysplasia ossificans progressiva
7
MAPK14
💬
7. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
[62]
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[62]
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
7. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
Losmapimod
[2]
113
113
,
222
💬
7. MAPK14
×
Disease ID
Name
113
Muscular dystrophy
222
Primary nephrotic syndrome
8
MAPK14
💬
8. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
[62]
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[62]
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
8. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
Neflamapimod
[1]
8
8
💬
8. MAPK14
×
Disease ID
Name
8
Huntington disease
9
IL17RA
💬
9. IL17RA
×
Name
Full Name
IL17RA
interleukin 17 receptor A
[3]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
IL-17 signaling pathway
,
Alcoholic liver disease
Brodalumab
Brodalumab
💬
9. IL17RA
×
Name
Other Names
Brodalumab
Brodalumab (USAN)
Brodalumab (genetical recombination) (JAN)
Siliq (TN)
Brodalumab
[2]
37
37
,
51
💬
9. IL17RA
×
Disease ID
Name
37
Generalised pustular psoriasis
51
Scleroderma
10
IFNA1
💬
10. IFNA1
×
Name
Full Name
IFNA1
interferon alpha 1
[25]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
Cytosolic DNA-sensing pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Alcoholic liver disease
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Autoimmune thyroid disease
,
Lipid and atherosclerosis
[25]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Toll-like rece
...
Rontalizumab
Rontalizumab
💬
10. IFNA1
×
Name
Other Names
Rontalizumab
Rontalizumab (USAN/INN)
Rontalizumab
[1]
49
49
💬
10. IFNA1
×
Disease ID
Name
49
Systemic lupus erythematosus